The use of botulinum toxin type A treatment in children with spasticity

B Sarioglu, G Serdaroglu, S Tutuncuoglu, EA Ozer - Pediatric neurology, 2003 - Elsevier
The current modalities in managing spastic children have some limitations; thus, alternative
therapeutic agents are in need. The purpose of this study is to investigate whether …

Pharmacotherapy of spasticity in children with cerebral palsy

A Verrotti, R Greco, A Spalice, F Chiarelli, P Iannetti - Pediatric neurology, 2006 - Elsevier
Spasticity is one of the most common symptoms presented by neurologic patients. Apart
from surgical management, drug therapy is an important treatment of children suffering from …

Botulinum toxin type a neuromuscular blockade in the treatment of equinus foot deformity in cerebral palsy: a multicenter, open-label clinical trial

LA Koman, A Brashear, S Rosenfeld, H Chambers… - …, 2001 - publications.aap.org
Background. Focal spasticity of the gastrocnemius-soleus muscles causes equinus gait in
children with cerebral palsy (CP). Botulinum toxin type A (BTX-A), a neuromuscular blocking …

Botulinum toxin A injection for spasticity in diplegic-type cerebral palsy

O El, O Peker, C Kosay, L Iyilikci… - Journal of child …, 2006 - journals.sagepub.com
Botulinum toxin type A can be both safe and effective in relieving spasticity in pediatric
patients with cerebral palsy. In our prospective study, we evaluated the functional effect of …

Functional outcomes of intramuscular botulinum toxin type a and occupational therapy in the upper limbs of children with cerebral palsy: a randomized controlled trial

M Wallen, SJ O'Flaherty, MCA Waugh - Archives of physical medicine and …, 2007 - Elsevier
Wallen M, O'Flaherty SJ, Waugh MC. Functional outcomes of intramuscular botulinum toxin
type A and occupational therapy in the upper limbs of children with cerebral palsy: a …

Adductor spasticity in children with cerebral palsy and treatment with botulinum toxin type A: the parents' view of functional outcome

F Heinen, M Linder, V Mall, J Kirschner… - European Journal of …, 1999 - Wiley Online Library
Botulinum toxin type A (BTX‐A) has been used successfully to manage spasticity in children
with cerebral palsy. Little has been done to evaluate treatment outcome and satisfaction …

Botulinum toxin in children with cerebral palsy

P Singhi, M Ray - The Indian Journal of Pediatrics, 2004 - Springer
Botulinum toxin is a neurotoxin that blocks the synaptic release of acetylcholine from
cholinergic nerve terminals mainly at the neuromuscular junction, resulting in irreversible …

Botulinum toxin type A treatment in children with cerebral palsy: evaluation of treatment success or failure by means of goal attainment scaling

K Desloovere, V Schörkhuber, K Fagard… - european journal of …, 2012 - Elsevier
BACKGROUND: There is considerable variability in the amount of response to BTX-A
treatment between and within patients with cerebral palsy (CP). AIMS: The purpose of this …

Botulinum toxin type A injections in the spastic upper extremity of children with hemiplegia: child characteristics that predict a positive outcome

D Fehlings, M Rang, J Glazier… - European Journal of …, 2001 - Wiley Online Library
Evidence is increasing to suggest that botulinum toxin type A (BTX‐A) plays a role in the
management of upper extremity spasticity in the paediatric population. However, little …

Botulinum toxin type A in children and adolescents with severe cerebral palsy: a retrospective chart review

R Mesterman, JW Gorter, A Harvey… - Journal of Child …, 2014 - journals.sagepub.com
This retrospective cohort study reviewed set goals and their outcomes of children and
adolescents with severe cerebral palsy who received botulinum toxin A in 2008 and 2009 …