Nanoparticles for cancer gene therapy: Recent advances, challenges, and strategies
Compared to conventional treatments, gene therapy offers a variety of advantages for
cancer treatment including high potency and specificity, low off-target toxicity, and delivery of …
cancer treatment including high potency and specificity, low off-target toxicity, and delivery of …
Production and clinical development of nanoparticles for gene delivery
Gene therapy is a promising strategy for specific treatment of numerous gene-associated
human diseases by intentionally altering the gene expression in pathological cells. A …
human diseases by intentionally altering the gene expression in pathological cells. A …
Nanoparticles for nucleic acid delivery: Applications in cancer immunotherapy
AJ Mukalel, RS Riley, R Zhang, MJ Mitchell - Cancer letters, 2019 - Elsevier
Immunotherapy has recently emerged as a powerful tool for cancer treatment. Early clinical
successes from cancer immunotherapy have led to a growing list of FDA approvals, and …
successes from cancer immunotherapy have led to a growing list of FDA approvals, and …
Nanoparticle drug delivery systems for synergistic delivery of tumor therapy
D Chen, X Liu, X Lu, J Tian - Frontiers in Pharmacology, 2023 - frontiersin.org
Nanoparticle drug delivery systems have proved anti-tumor effects; however, they are not
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …
Targeted polymeric nanoparticles for cancer gene therapy
In this article, advances in designing polymeric nanoparticles for targeted cancer gene
therapy are reviewed. Characterization and evaluation of biomaterials, targeting ligands …
therapy are reviewed. Characterization and evaluation of biomaterials, targeting ligands …
Will nanotechnology bring new hope for gene delivery?
JKL Wong, R Mohseni, AA Hamidieh… - Trends in …, 2017 - cell.com
The high mortality rates of cancer patients receiving standard treatments emphasize the
crucial need for alternative treatments. One promising strategy is to use organic …
crucial need for alternative treatments. One promising strategy is to use organic …
Nanoparticle delivery systems for DNA/RNA and their potential applications in nanomedicine
H Shen, X Huang, J Min, S Le, Q Wang… - Current topics in …, 2019 - ingentaconnect.com
The rapid development of nanotechnology has a great influence on the fields of biology,
physiology, and medicine. Over recent years, nanoparticles have been widely presented as …
physiology, and medicine. Over recent years, nanoparticles have been widely presented as …
Nanoparticles for gene delivery: therapeutic and toxic effects
Gene therapy has drawn significant attention as a potential method for treating both acute
illnesses and chronic diseases. Current research efforts have focused on developing …
illnesses and chronic diseases. Current research efforts have focused on developing …
Recent advances in nanoparticle-based cancer drug and gene delivery
Effective and safe delivery of anticancer agents is among the major challenges in cancer
therapy. The majority of anticancer agents are toxic to normal cells, have poor bioavailability …
therapy. The majority of anticancer agents are toxic to normal cells, have poor bioavailability …
Non-viral nucleic acid containing nanoparticles as cancer therapeutics
KL Kozielski, Y Rui, JJ Green - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: The delivery of nucleic acids such as DNA and short interfering RNA (siRNA) is
promising for the treatment of many diseases, including cancer, by enabling novel biological …
promising for the treatment of many diseases, including cancer, by enabling novel biological …