Wearable inertial sensors provide reliable biomarkers of disease severity in multiple sclerosis: a systematic review and meta-analysis

A Vienne-Jumeau, F Quijoux, PP Vidal… - Annals of physical and …, 2020 - Elsevier
Background Gait impairment is a hallmark of multiple sclerosis (MS). InertiaLocoGraphy, the
quantification of gait with inertial measurement units (IMUs), has been found useful to detect …

Value of gait analysis for measuring disease severity using inertial sensors in patients with multiple sclerosis: protocol for a systematic review and meta-analysis

A Vienne-Jumeau, F Quijoux, PP Vidal, D Ricard - Systematic Reviews, 2019 - Springer
Background Gait impairment is a hallmark of multiple sclerosis (MS) which significantly
endangers the quality of life of the individual. Inertial measurement units (IMUs) are small …

Is a wearable sensor-based characterisation of gait robust enough to overcome differences between measurement protocols? A multi-centric pragmatic study in …

L Angelini, I Carpinella, D Cattaneo, M Ferrarin… - Sensors, 2019 - mdpi.com
Inertial measurement units (IMUs) allow accurate quantification of gait impairment of people
with multiple sclerosis (pwMS). Nonetheless, it is not clear how IMU-based metrics might be …

Wearable inertial sensors are highly sensitive in the detection of gait disturbances and fatigue at early stages of multiple sclerosis

R Müller, D Hamacher, S Hansen, P Oschmann… - BMC neurology, 2021 - Springer
Background The aim of the current study was to examine multiple gait parameters obtained
by wearable inertial sensors and their sensitivity to clinical status in early multiple sclerosis …

Clinical assessment of gait in individuals with multiple sclerosis using wearable inertial sensors: Comparison with patient-based measure

M Pau, S Caggiari, A Mura, F Corona, B Leban… - Multiple sclerosis and …, 2016 - Elsevier
Background This study aims to verify the feasibility of use of wearable accelerometers in an
ambulatory environment to assess spatiotemporal parameters of gait in people with Multiple …

Assessment and classification of early-stage multiple sclerosis with inertial sensors: comparison against clinical measures of disease state

BR Greene, S Rutledge, I McGurgan… - IEEE journal of …, 2015 - ieeexplore.ieee.org
A cross-sectional study on patients with early-stage multiple sclerosis (MS) was conducted
to examine the reliability of manual and automatic mobility measures derived from shank …

Innovative multidimensional gait evaluation using IMU in multiple sclerosis: introducing the semiogram

C Voisard, N de l'Escalopier, A Vienne-Jumeau… - Frontiers in …, 2023 - frontiersin.org
Background Quantifying gait using inertial measurement units has gained increasing
interest in recent years. Highly degraded gaits, especially in neurological impaired patients …

Validity of an inertial sensor-based system for the assessment of spatio-temporal parameters in people with multiple sclerosis

A Zahn, V Koch, L Schreff, P Oschmann… - Frontiers in …, 2023 - frontiersin.org
Background Gait variability in people with multiple sclerosis (PwMS) reflects disease
progression or may be used to evaluate treatment response. To date, marker-based camera …

Free-living and laboratory gait characteristics in patients with multiple sclerosis

FA Storm, KPS Nair, AJ Clarke, JM Van der Meulen… - PloS one, 2018 - journals.plos.org
Background Wearable sensors offer the potential to bring new knowledge to inform
interventions in patients affected by multiple sclerosis (MS) by thoroughly quantifying gait …

Disability and fatigue can be objectively measured in multiple sclerosis

C Motta, E Palermo, V Studer, M Germanotta… - PLoS …, 2016 - journals.plos.org
Background The available clinical outcome measures of disability in multiple sclerosis are
not adequately responsive or sensitive. Objective To investigate the feasibility of inertial …