Nephrotoxin exposure and acute kidney injury in adults

BR Griffin, L Wendt, M Vaughan-Sarrazin… - Clinical Journal of the …, 2023 - journals.lww.com
Background Rates of nephrotoxic AKI are not well described in adults due to lack of a clear
definition, debate over which drugs should be considered nephrotoxins, and illness-related …

Electronic health record identification of nephrotoxin exposure and associated acute kidney injury

SL Goldstein, E Kirkendall, H Nguyen, JK Schaffzin… - …, 2013 - publications.aap.org
BACKGROUND AND OBJECTIVE: Nephrotoxic medication exposure represents a common
cause of acute kidney injury (nephrotoxin-AKI) in hospitalized children. Systematic serum …

Administrative data misclassifies and fails to identify nephrotoxin-associated acute kidney injury in hospitalized children

JK Schaffzin, CN Dodd, H Nguyen… - Hospital …, 2014 - publications.aap.org
Objectives: Nephrotoxin exposure is a common cause of acute kidney injury (AKI) in
hospitalized children. AKI detection relies on regular serum creatinine (SCr) screening …

[HTML][HTML] A sustained quality improvement program reduces nephrotoxic medication-associated acute kidney injury

SL Goldstein, T Mottes, K Simpson, C Barclay… - Kidney international, 2016 - Elsevier
Exposure to nephrotoxic medication is among the most common causes of acute kidney
injury (AKI) in hospitalized patients. Here we conducted a prospective quality improvement …

Drug-induced acute kidney injury: a focus on risk assessment for prevention

SL Kane-Gill, SL Goldstein - Critical care clinics, 2015 - criticalcare.theclinics.com
Crit Care Clin 31 (2015) 675–684 http://dx. doi. org/10.1016/j. ccc. 2015.06. 005 criticalcare.
theclinics. com 0749-0704/15/$–see front matter© 2015 Elsevier Inc. All rights reserved. the …

Nephrotoxin exposure in the 3 years following hospital discharge predicts development or worsening of chronic kidney disease among acute kidney injury survivors

DJ Schreier, AD Rule, KB Kashani, KC Mara… - American journal of …, 2022 - karger.com
Introduction: Survivors of acute kidney injury (AKI) are at high risk of progression to chronic
kidney disease (CKD), for which drugs may be a modifiable risk factor. Methods: We …

Nephrotoxins and nephrotoxic acute kidney injury

AM Uber, SM Sutherland - Pediatric Nephrology, 2020 - Springer
Although the concept of nephrotoxicity has been recognized for more than 80 years, interest
in nephrotoxins has intensified dramatically over the past two decades. Much of this …

Baby NINJA (Nephrotoxic Injury Negated by Just-in-Time Action): reduction of nephrotoxic medication-associated acute kidney injury in the neonatal intensive care …

C Stoops, S Stone, E Evans, L Dill, T Henderson… - The Journal of …, 2019 - Elsevier
Objective (s) To test if acute kidney injury (AKI) is preventable in patients in the neonatal
intensive care unit and if infants at high-risk of nephrotoxic medication-induced AKI can be …

Preventing acute kidney injury through nephrotoxin management

MA Perazella, FP Wilson - Nature Reviews Nephrology, 2016 - nature.com
Nephrotoxin-induced acute kidney injury (AKI) is a considerable risk among hospitalized
children. The development and use of a proactive, nephrotoxin screening system seems to …

Nephrotoxin exposure and acute kidney injury in critically ill children undergoing congenital cardiac surgery

AM Uber, ME Montez-Rath, DM Kwiatkowski… - Pediatric …, 2018 - Springer
Background Though acute kidney injury (AKI) is often multifactorial, investigators are now
emphasizing the specific contribution of nephrotoxins. This study examines the …