心血管药物临床试验评价方法的建议

刘国仗, 吴宁, 胡大一, 陶萍, 诸骏仁, 郭林妮… - 中华心血管病 …, 1998 - cqvip.com
Ⅳ. 抗心律失常药心律失常可以发生在器质性心脏病或无明显心脏病的患者.
心律失常发生机制复杂, 临床上常分为缓慢或快速心律失常. 缓慢心律失常引起临床症状或伴有 …

Lessons learned from recent cardiovascular clinical trials: Part I

DL DeMets, RM Califf - Circulation, 2002 - Am Heart Assoc
HIV-positive patients. The validity of a composite depends on the validity of its individual
components. Unfortunately, potential surrogates have been inadequately validated in most …

Interpretation of outcomes of antiarrhythmic clinical trials: design features and population impact

RJ Myerburg, R Mitrani, A Interian Jr, A Castellanos - Circulation, 1998 - Am Heart Assoc
monly used in economic analyses of efficacy. Although the expression of benefit in terms of
cost per year is a source of conflict between ethics and economics, the clinical counterpart of …