Background There is a metabolic pathway by which mammals can convert the omega-3 (n-
3) essential fatty acid α-linolenic acid (ALA) into longer-chain n-3 polyunsaturated fatty acids …

High linoleic acid (LA) intakes have been suggested to reduce α-linolenic acid [ALA, 18: 3 (n-
3)] metabolism to eicosapentaenoic acid [EPA, 20: 5 (n-3)] and docosahexaenoic acid [DHA …

This paper presents a systematic review of human studies investigating the effect of altering
dietary omega-3 polyunsaturated fatty acid (n-3 PUFA) alpha-linolenic acid (ALA) and …

Abstract α‐linolenic acid (αLNA) conversion into the functionally important ω‐3
polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (EPA), and docosahexaenoic …

Our aim was to study the effects of increased dietary intake of α-linolenic acid (ALA),
eicosapentaenoic acid (EPA), or docosahexaenoic acid (DHA) on serum lipids and LDL fatty …

Background: Intakes of n–3 (omega-3) polyunsaturated fatty acids (PUFAs) are important for
health. Because fish is the major source of eicosapentaenoic acid (EPA) and …

Dietary n-3 PUFA have many beneficial effects on cell and tissue function and on human
health. In mammals the n-3 essential fatty acid α-linolenic acid (ALNA) can be converted into …

This review summarises and evaluates current knowledge of α‐linolenic acid (αLNA)
metabolism in adult humans. The principal biological role of αLNA appears to be as a …

α-Linolenic acid (αLNA; 18: 3n-3) is essential in the human diet, probably because it is the
substrate for the synthesis of longer-chain, more unsaturated n-3 fatty acids, principally EPA …

Background: Dietary α-linolenic acid (ALA) can be converted to long-chain n− 3
polyunsaturated fatty acids (PUFAs) in humans and may reproduce some of the beneficial …