Plant-derived polyphenols are known to possess anti-inflammatory and antioxidant effects.
In recent years, several studies have investigated their potential benefits for treating chronic …

Degeneration of retinal pigment epithelial (RPE) cells is a clinical hallmark of age-related
macular degeneration (AMD), the leading cause of blindness among aged people in the …

purpose. To determine whether specific dietary and synthetic flavonoids can protect human
retinal pigment epithelial (RPE) cells from oxidative-stress–induced death. methods. The …

Several studies have reported the efficacy and safety of polyphenols in human health;
however, the verification of their efficacy remains insufficient. The aim of this study was to …

Oxidative damage and inflammation are related to the pathogenesis of age-related macular
degeneration (AMD). Epidemiologic studies suggest that insufficient dietary lutein and …

Retinal pigment epithelium (RPE) plays the principal role in age-related macular
degeneration (AMD), a progressive eye disease with no cure and limited therapeutical …

Although fisetin, a natural flavonoid, was known to inhibit proliferation, carcinogenesis and
inflammation, the underlying anti-inflammatory mechanism of fistein still remains unclear …

Purpose: This study was conducted to determine whether paeoniflorin (PF) could prevent
H2O2-induced oxidative stress in ARPE-19 cells and to elucidate the molecular pathways …

Fisetin is a kind of bioactive flavonol, widely present in various fruits such as strawberries
and apples, and is known to act as a potent free radical scavenger. However, the …

The protection of retinal pigment epithelium (RPE) injury plays an important role in the
prevention of or in delaying the pathological progress of retinal degeneration diseases, like …