Citrulline protects human retinal pigment epithelium from hydrogen peroxide and iron/ascorbate induced damages
C Hassel, M Couchet, N Jacquemot… - Journal of Cellular …, 2022 - Wiley Online Library
Oxidative stress plays an important role in the ageing of the retina and in the pathogenesis
of retinal diseases such as age‐related macular degeneration (ARMD). Hydrogen peroxide …
of retinal diseases such as age‐related macular degeneration (ARMD). Hydrogen peroxide …
[HTML][HTML] Cytoprotective effects of natural highly bio-available vegetable derivatives on human-derived retinal cells
I Munia, L Gafray, MA Bringer, P Goldschmidt… - Nutrients, 2020 - mdpi.com
Retinal pigment epithelial cells are crucial for retina maintenance, making their
cytoprotection an excellent way to prevent or slow down retinal degeneration. In addition …
cytoprotection an excellent way to prevent or slow down retinal degeneration. In addition …
[HTML][HTML] Ocular inflammation and endoplasmic reticulum stress are attenuated by supplementation with grape polyphenols in human retinal pigmented epithelium …
Inflammation and endoplasmic reticulum (ER) stress are common denominators for vision-
threatening diseases such as diabetic retinopathy and age-related macular degeneration …
threatening diseases such as diabetic retinopathy and age-related macular degeneration …
New lipophenols prevent carbonyl and oxidative stresses involved in macular degeneration
E Moine, M Boukhallat, D Cia, N Jacquemot… - Free Radical Biology …, 2021 - Elsevier
Dry age-related macular degeneration and Stargardt disease undergo a known toxic
mechanism caused by carbonyl and oxidative stresses (COS). This is responsible for …
mechanism caused by carbonyl and oxidative stresses (COS). This is responsible for …
[HTML][HTML] Flavonoids protect retinal ganglion cells from oxidative stress–induced death
P Maher, A Hanneken - Investigative ophthalmology & visual …, 2005 - arvojournals.org
purpose. Mounting evidence suggests that oxidative stress contributes to the pathogenesis
of many ocular diseases, including glaucoma and diabetic retinopathy. No treatments are …
of many ocular diseases, including glaucoma and diabetic retinopathy. No treatments are …
Combination of Lutein and Zeaxanthin, and DHA Regulated Polyunsaturated Fatty Acid Oxidation in H2O2-Stressed Retinal Cells
HH Leung, JM Galano, C Crauste, T Durand… - Neurochemical …, 2020 - Springer
Photochemical and oxidative damages in retinal pigment epithelial (RPE) cells are key
events in the pathogenesis of age-related macular degeneration. Polyunsaturated fatty acids …
events in the pathogenesis of age-related macular degeneration. Polyunsaturated fatty acids …
Plant flavonol quercetin and isoflavone biochanin A differentially induce protection against oxidative stress and inflammation in ARPE-19 cells
NMM Saviranta, L Veeroos, LJ Granlund… - Food Research …, 2011 - Elsevier
In this work, differential ability of plant flavonol quercetin and plant isoflavone biochanin A to
modulate oxidative stress and inhibit inflammation-related responses was investigated using …
modulate oxidative stress and inhibit inflammation-related responses was investigated using …
[HTML][HTML] Inflammation, a double-edge sword for cancer and other age-related diseases
Increasing evidence from diverse sources during the past several years has indicated that
long-term, low level, chronic inflammation mediates several chronic diseases including …
long-term, low level, chronic inflammation mediates several chronic diseases including …
[HTML][HTML] Functional diversity of flavonoids in the inhibition of the proinflammatory NF-κB, IRF, and Akt signaling pathways in murine intestinal epithelial cells
The molecular understanding of nutritional factors in the process of host factor–mediated
activation of the intestinal epithelium may play an important role in the assessment of …
activation of the intestinal epithelium may play an important role in the assessment of …
Fisetin derivatives exhibit enhanced anti-inflammatory activity and modulation of endoplasmic reticulum stress
DC da Silva, PJ Jervis, JA Martins, P Valentão… - International …, 2023 - Elsevier
Inflammation and endoplasmic reticulum (ER) stress are often hand in hand in the context of
chronic disease. Both are activated upon perceived disturbances in homeostasis, being …
chronic disease. Both are activated upon perceived disturbances in homeostasis, being …