Xenogenetic evolutionary of integrons promotes the environmental pollution of antibiotic resistance genes—Challenges, progress and prospects

R An, Y Qi, XX Zhang, L Ma - Water Research, 2023 - Elsevier
Environmental pollution of antibiotic resistance genes (ARGs) has been a great public
concern. Integrons, as mobile genetic elements, with versatile gene acquisition systems …

The prevalence of integrons as the carrier of antibiotic resistance genes in natural and man-made environments

L Ma, AD Li, XL Yin, T Zhang - Environmental science & …, 2017 - ACS Publications
Class 1 integrase int I1 has been considered as a good proxy for anthropogenic pollution
because of being linked to genes conferring resistance to antibiotics. The gene cassettes of …

Integrons and antibiotic resistance genes in water-borne pathogens: threat detection and risk assessment

M Kaushik, S Kumar, RK Kapoor… - Journal of medical …, 2019 - microbiologyresearch.org
Antibiotic-resistant genes (ARGs) are regarded as emerging environmental pollutants and
pose a serious health risk to the human population. Integrons are genetic elements that are …

Class 1 integron and related antimicrobial resistance gene dynamics along a complex freshwater system affected by different anthropogenic pressures

G Corno, T Ghaly, R Sabatino, EM Eckert… - Environmental …, 2023 - Elsevier
The risk for human health posed by polluted aquatic environments, and especially those
carrying antibiotic resistance genes (ARGs) of clinical interest, is still debated. This is …

Dissemination of antibiotic resistance genes (ARGs) via integrons in Escherichia coli: a risk to human health

S Zhang, M Abbas, MU Rehman, Y Huang, R Zhou… - Environmental …, 2020 - Elsevier
With the induction of various emerging environmental contaminants such as antibiotic
resistance genes (ARGs), environment is considered as a key indicator for the spread of …

Integron involvement in environmental spread of antibiotic resistance

T Stalder, O Barraud, M Casellas, C Dagot… - Frontiers in …, 2012 - frontiersin.org
The spread of antibiotic-resistant bacteria is a growing problem and a public health issue. In
recent decades, various genetic mechanisms involved in the spread of resistance genes …

Investigating the antibiotic resistance genes and their potential risks in the megacity water environment: A case study of Shenzhen Bay Basin, China

H Liang, J Huang, Y Tao, U Klümper… - Journal of Hazardous …, 2024 - Elsevier
Antibiotic resistance genes (ARGs) constitute emerging pollutants and pose serious risks to
public health. Anthropogenic activities are recognized as the main driver of ARG …

High-throughput screening of antimicrobial resistance genes and their association with class 1 integrons in urban rivers in Japan

I Kasuga, K Nagasawa, M Suzuki, F Kurisu… - Frontiers in …, 2022 - frontiersin.org
Antimicrobial resistance (AMR) is a serious public health concern. Many countries have
implemented AMR surveillance programs for humans and animals, but a scheme for …

Quantitative and qualitative impact of hospital effluent on dissemination of the integron pool

T Stalder, O Barraud, T Jové, M Casellas… - The ISME …, 2014 - academic.oup.com
There is increasing evidence that human activity, and especially the resulting effluent, has a
major role in the dissemination of bacterial antibiotic-resistance determinants in the …

Molecular diversity of class 2 integrons in antibiotic-resistant gram-negative bacteria found in wastewater environments in China

R Xia, Y Ren, X Guo, H Xu - Ecotoxicology, 2013 - Springer
The molecular architecture of class 2 integrons among gram-negative bacteria from
wastewater environments was investigated in Jinan, China. Out of the 391 antibiotic …