Three novel genetic variants in the FAM110D, CACNA1A, and NLRP12 genes are associated with susceptibility to hypertension among Dai people
L Zhang, Y Sun, X Zhang, X Shan, J Li… - American journal of …, 2021 - academic.oup.com
BACKGROUND Although the genetic factors associated with hypertension remain unknown,
genetic variations in genes related to ion channels, inflammation, and the cell cycle may …
genetic variations in genes related to ion channels, inflammation, and the cell cycle may …
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension
Hypertension is a common disorder and the leading risk factor for cardiovascular disease
and premature deaths worldwide. Genome-wide association studies (GWASs) in the …
and premature deaths worldwide. Genome-wide association studies (GWASs) in the …
A three-stage genome-wide association study combining multilocus test and gene expression analysis for young-onset hypertension in Taiwan Han Chinese
KM Chiang, HC Yang, YJ Liang… - American journal of …, 2014 - academic.oup.com
BACKGROUND Although many large-scale genome-wide association studies (GWASs)
have been performed, only a few studies have successfully identified replicable, large …
have been performed, only a few studies have successfully identified replicable, large …
An exploration of gene‐gene interactions and their effects on hypertension
Y Meng, S Groth, JR Quinn… - International journal of …, 2017 - Wiley Online Library
Hypertension tends to perpetuate in families and the heritability of hypertension is estimated
to be around 20–60%. So far, the main proportion of this heritability has not been found by …
to be around 20–60%. So far, the main proportion of this heritability has not been found by …
[HTML][HTML] Identification of polymorphisms in 12q24. 1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association …
Y Yamada, J Sakuma, I Takeuchi, Y Yasukochi… - Oncotarget, 2017 - ncbi.nlm.nih.gov
We performed exome-wide association studies to identify genetic variants that influence
systolic or diastolic blood pressure or confer susceptibility to hypertension in Japanese. The …
systolic or diastolic blood pressure or confer susceptibility to hypertension in Japanese. The …
Association of common variants in/near six genes (ATP2B1, CSK, MTHFR, CYP17A1, STK39 and FGF5) with blood pressure/hypertension risk in Chinese children
B Xi, Y Shen, X Zhao, GR Chandak, H Cheng… - Journal of Human …, 2014 - nature.com
Recent genome-wide association studies have identified several single-nucleotide
polymorphisms (SNPs) that are associated with blood pressure (BP)/hypertension. In this …
polymorphisms (SNPs) that are associated with blood pressure (BP)/hypertension. In this …
A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits
Hypertension is caused by the interaction of environmental and genetic factors. The
condition which is very common, with about 18% of the adult Hong Kong Chinese …
condition which is very common, with about 18% of the adult Hong Kong Chinese …
Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as Hypertension Susceptibility Genes in Han Chinese with a Genome-Wide Gene-Based Association Study
Hypertension is a complex disorder with high prevalence rates all over the world. We
conducted the first genome-wide gene-based association scan for hypertension in a Han …
conducted the first genome-wide gene-based association scan for hypertension in a Han …
High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project
N Kato, T Miyata, Y Tabara, T Katsuya… - Human Molecular …, 2008 - academic.oup.com
Essential hypertension is one of the most common, complex diseases, of which
considerable efforts have been made to unravel the pathophysiological mechanisms. Over …
considerable efforts have been made to unravel the pathophysiological mechanisms. Over …
A two-stage whole-genome gene expression association study of young-onset hypertension in Han Chinese population of Taiwan
KM Chiang, HC Yang, WH Pan - Scientific Reports, 2018 - nature.com
Hypertension is an important public health problem in the world. Since the intermediate
position of the gene expression between genotype and phenotype makes it suitable to link …
position of the gene expression between genotype and phenotype makes it suitable to link …