A genome-wide association study identifies a novel candidate locus at the DLGAP1 gene with susceptibility to resistant hypertension in the Japanese population
Y Takahashi, K Yamazaki, Y Kamatani, M Kubo… - Scientific Reports, 2021 - nature.com
Numerous genetic variants associated with hypertension and blood pressure are known, but
there is a paucity of evidence from genetic studies of resistant hypertension, especially in …
there is a paucity of evidence from genetic studies of resistant hypertension, especially in …
The univariation and multiple linear regression analyses for seventeen SNPs in thirteen cardiovascular disease-predisposing genes and blood pressure in Chinese …
M Tang, Y Dai, Y Huang, X Cai, X Tian… - Clinical and Experimental …, 2008 - Taylor & Francis
Blood pressure (BP) is a complex trait regulated by the interaction among multiple
physiologic regulatory systems, likely involving numerous genes that lead to inconsistent …
physiologic regulatory systems, likely involving numerous genes that lead to inconsistent …
Longitudinal exome-wide association study to identify genetic susceptibility loci for hypertension in a Japanese population
Y Yasukochi, J Sakuma, I Takeuchi, K Kato… - … & molecular medicine, 2017 - nature.com
Genome-wide association studies have identified various genetic variants associated with
complex disorders. However, these studies have commonly been conducted in a cross …
complex disorders. However, these studies have commonly been conducted in a cross …
Replication of the top 10 most significant polymorphisms from a large blood pressure genome-wide association study of northeastern Han Chinese East Asians
Y Qi, H Zhao, Y Wang, Y Wang, C Lu, Y Xiao… - Hypertension …, 2014 - nature.com
The replication of genome-wide significant association signals in independent populations
is a practical approach for characterizing gene-disease relationships. Therefore, we sought …
is a practical approach for characterizing gene-disease relationships. Therefore, we sought …
Replication of an African-American GWAS on blood pressure and hypertension in the Korean population
HS Jin, KW Hong, JE Lim, B Oh - Genes & Genomics, 2011 - Springer
Hypertension is a complex disease that is caused by the interaction of multiple genetic and
environmental risk factors, affecting 30% adult in industrialized countries. The identification …
environmental risk factors, affecting 30% adult in industrialized countries. The identification …
Genome-wide association study meta-analysis of long-term average blood pressure in East Asians
Background—Genome-wide single marker and gene-based meta-analyses of long-term
average (LTA) blood pressure (BP) phenotypes may reveal novel findings for BP. Methods …
average (LTA) blood pressure (BP) phenotypes may reveal novel findings for BP. Methods …
Associations of epithelial sodium channel genes with blood pressure: the GenSalt study
F Liu, X Yang, X Mo, J Huang, J Chen… - Journal of human …, 2015 - nature.com
In order to investigate the associations of SCNN1A, SCNN1G and SCNN1B genes with
blood pressure (BP) in the Han Chinese population, we included 2880 participants did not …
blood pressure (BP) in the Han Chinese population, we included 2880 participants did not …
Genome-wide gene–sodium interaction analyses on blood pressure: the genetic epidemiology network of salt-sensitivity study
We performed genome-wide analyses to identify genomic loci that interact with sodium to
influence blood pressure (BP) using single-marker–based (1 and 2 df joint tests) and gene …
influence blood pressure (BP) using single-marker–based (1 and 2 df joint tests) and gene …
Candidate gene polymorphisms influence the susceptibility to salt sensitivity of blood pressure in a han Chinese population: risk factors as mediators
Y Xie, Z Liu, K Liu, H Qi, W Peng, H Cao, X Liu… - Frontiers in …, 2021 - frontiersin.org
Genome-wide association studies suggest that there is a significant genetic susceptibility to
salt sensitivity of blood pressure (SSBP), but it still needs to be verified in varied and large …
salt sensitivity of blood pressure (SSBP), but it still needs to be verified in varied and large …
Influence of obesity on association between genetic variants identified by genome-wide association studies and hypertension risk in Chinese children
B Xi, X Zhao, GR Chandak, Y Shen… - American journal of …, 2013 - academic.oup.com
BACKGROUND Childhood hypertension is a complex disease influenced by both genetic
and environmental factors. We aimed to examine how obesity status influences the …
and environmental factors. We aimed to examine how obesity status influences the …