Essential hypertension (EH) is a leading risk condition for cardiovascular and renal
complications. While multiple genes are associated with EH, little is known about its genetic …

Background High blood pressure is common and comorbid with type 2 diabetes (T2D).
Almost 50% of patients with T2D have high blood pressure. Patients with both conditions of …

Rationale: Hypertension affects≈ 30% of adults in industrialized countries and is the major
risk factor for cardiovascular disease. Objective: We sought to study the genetic effect of …

Genetic risk factors for hypertension may have age or gender specificity and pleiotropic
effects. This study aims to measure the risk of genetic and non-genetic factors in the …

Hypertension is a leading risk factor of cardiovascular disease and mortality in the
population worldwide. Recently, hundreds of genomic loci were reported for hypertension by …

High blood pressure is a major risk factor for cardiovascular disease and premature death.
However, there is limited knowledge on specific causal genes and pathways. To better …

Increased pulse pressure (PP) and decreased mean arterial pressure (MAP) are strong
prognostic predictors of adverse cardiovascular events. Recently, the International …

Hypertension is one of the most common complex genetic disorders. We have described
previously 38 single nucleotide polymorphisms (SNPs) with suggestive association with …

Background: The association between the CYP17A1 and ATP2B1 SNPs and essential
hypertension (referred to as hypertension) is far from being consistent. In addition to the …

Background: Recent genome-wide association studies (GWASs) have identified 30 genetic
loci that regulate blood pressure, increasing our understanding of the cause of hypertension …