Minimizing and managing treatment-associated complications in patients with chronic lymphocytic leukemia

E Iskierka-Jażdżewska, T Robak - Expert Review of Hematology, 2020 - Taylor & Francis
Introduction: During recent years, therapy in chronic lymphocytic leukemia (CLL) has
changed dramatically. The introduction of small molecule inhibitors has shown remarkable …

Chronic Lymphocytic Leukemia: Management of Adverse Events in the Era of Targeted Agents

A Galitzia, M Maccaferri, FR Mauro, R Murru… - Cancers, 2024 - mdpi.com
Simple Summary Targeted agents, such as Bruton's Tyrosine Kinase inhibitors and BCL-2
inhibitors, have transformed the treatment landscape for Chronic Lymphocytic Leukemia …

Redefining efficacy and safety endpoints for chronic lymphocytic leukemia in the era of targeted therapy

S Molica - Expert Review of Hematology, 2023 - Taylor & Francis
The therapeutic landscape for chronic lymphocytic leukemia (CLL) has dramatically
changed during the past ten years with the shift from conventional chemo-immunotherapy …

Pharmacological management of chronic lymphocytic leukemia: current and emerging therapies

IJ Huang, GT Baek, C Siu… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL),
characterized by its monoclonal lymphoproliferative nature, is an indolent but incurable …

Old and new drugs for chronic lymphocytic leukemia: Lights and shadows of real-world evidence

M Marchetti, C Vitale, GM Rigolin, A Vasile… - Journal of Clinical …, 2022 - mdpi.com
Several novel treatments for chronic lymphocytic leukemia (CLL) have been recently
approved based on the results of randomized clinical trials. However, real-world evidence …

Unresolved questions in selection of therapies for treatment-naïve chronic lymphocytic leukemia

R Bennett, MA Anderson, JF Seymour - Journal of Hematology & Oncology, 2023 - Springer
Background The treatment landscape for chronic lymphocytic leukemia (CLL) continues to
undergo considerable evolution. Optimal selection of initial therapy from multiple effective …

Balancing efficacy and toxicity of targeted agents currently used for the treatment of patients with chronic lymphocytic leukemia

FR Mauro, MD Caputo, S Rosati, S Pepe… - Expert Review of …, 2018 - Taylor & Francis
Introduction: In recent years, innovative mechanism-based drugs have enriched the
therapeutic armamentarium for patients with chronic lymphocytic leukemia (CLL) and are …

[HTML][HTML] Treatment discontinuation patterns for patients with chronic lymphocytic leukemia in real-world settings: results from a multi-center international study

M Shadman, BS Manzoor, K Sail, HH Tuncer… - … Myeloma and Leukemia, 2023 - Elsevier
Introduction This study assessed treatment discontinuation patterns and reasons among
chronic lymphocytic leukemia (CLL) patients initiating first-line (1L) and second-line (2L) …

Current perspectives on therapy for chronic lymphocytic leukemia

FT Awan, O Al-Sawaf, K Fischer… - American Society of …, 2020 - ascopubs.org
Therapy for chronic lymphocytic leukemia has improved dramatically over the past decade
with the introduction of new targeted therapies and a paradigm shift toward targeted …

Can early intervention with pharmacotherapy reduce the morbidity and mortality of chronic lymphocytic leukemia?

S Ma, LC Platanias - Expert opinion on pharmacotherapy, 2018 - Taylor & Francis
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western
society with an incidence of over 20,000 new cases per year in the United States. The two …