Chitosan as a biomaterial: Influence of degree of deacetylation on its physiochemical, material and biological properties

LJR Foster, S Ho, J Hook, M Basuki, H Marcal - PloS one, 2015 - journals.plos.org
Chitosan is a biomaterial with a range of current and potential biomedical applications.
Manipulation of chitosan degree of deacetylation (DDA) to achieve specific properties …

Deacetylation of Chitosan: Material Characterization and in vitro Evaluation via Albumin Adsorption and Pre-Osteoblastic Cell Cultures

Y Yuan, BM Chesnutt, WO Haggard, JD Bumgardner - Materials, 2011 - mdpi.com
Degree of deacetylation (DDA) and molecular weight (MW) of chitosans are important to
their physical and biological properties. In this study, two chitosans, HS (DDA= 73.3%) and …

In vitro characterization of chitosan scaffolds: influence of composition and deacetylation degree

R Seda Tığlı, A Karakeçili… - Journal of Materials …, 2007 - Springer
In this study, the influence of degree of deacetylation (DD) and composition on some
structural and biological properties of chitosan scaffolds were examined in vitro. 3D chitosan …

Cellular responses to chitosan in vitro: the importance of deacetylation

M Prasitsilp, R Jenwithisuk, K Kongsuwan… - Journal of materials …, 2000 - Springer
Chitin and chitosan (a deacetylated derivative of chitin) have been proposed for biomedical
applications because of their biocompatibility and abundance in nature. We have …

Effect of deacetylation time on the preparation, properties and swelling behavior of chitosan films

D Baskar, TSS Kumar - Carbohydrate polymers, 2009 - Elsevier
The effect of time during the deacetylation of chitin by hot alkali was studied to ascertain the
film forming ability of chitosan. Five types of chitosan films were prepared in a single step …

Controlling chitosan degradation properties in vitro and in vivo

JA Jennings - Chitosan Based Biomaterials Volume 1, 2017 - Elsevier
Among the many advantages of chitosan as an implant biomaterial, is controllable
degradability, which makes chitosan a unique biomaterial choice for tissue engineering and …

Characterization of chitosan films and effects on fibroblast cell attachment and proliferation

V Hamilton, Y Yuan, DA Rigney, AD Puckett… - Journal of Materials …, 2006 - Springer
Chitosan has been researched for implant and wound healing applications. However, there
are inconsistencies in reports on the tissue and fibroblast responses to chitosan materials …

In vitro and in vivo degradation of films of chitin and its deacetylated derivatives

K Tomihata, Y Ikada - Biomaterials, 1997 - Elsevier
Chitin was deacetylated to various extents with NaOH to obtain partially and thoroughly
deacetylated chitins. The specimens used in this study were deacetylated by 0 (chitin), 68.8 …

Physicochemical, mechanical and thermal properties of chitosan films with and without sorbitol

M Liu, Y Zhou, Y Zhang, C Yu, S Cao - International journal of biological …, 2014 - Elsevier
The effect of sorbitol on the physicochemical, mechanical and thermal properties of chitosan
films with different degrees of deacetylation (DD; ie, DD85% and DD95%) was investigated …

Chitosan as scaffold materials: Effects of molecular weight and degree of deacetylation

S Hsu, SW Whu, CL Tsai, YH Wu, HW Chen… - Journal of Polymer …, 2004 - Springer
In this study, we investigated in vitro the role of the degree of deacetylation and molecular
weight on some biological properties of chitosan films. The influence of different degree of …