Apoptosis is a crucial program of cell death that controls development and homeostasis of
multicellular organisms. The main initiators and executors of this process are the Cysteine …

Apoptosis or programmed cell death is an active form of cell death which is essential for
tissue homeostasis. Many proteins are involved in the molecular signal transduction of …

Apoptosis, a highly controlled mode of cell death, is utilized to eliminate superfluous, aged,
injured or infected cells from the body. Caspases, a family of aspartic acid-specific …

The cysteinyl aspartate-specific proteases (caspases) have been identified as key players in
the cellular process termed programmed cell death or apoptosis. During apoptosis, activated …

The process of apoptosis, or programmed cell death, is fundamental during normal
development and homeostasis and aberrant apoptosis has been implicated in a number of …

Nearly all physiological cell deaths in animals proceed by the process of apoptosis, during
which the dying cells vanish without a trace, silently cleared without any accompanying …

Apoptosis is an intrinsic cell-suicide programme, which ensures tissue homeostasis and
safeguards the organism by eliminating unnecessary and unwanted cells, or cells that may …

Caspases, a family of evolutionarily, conserved cysteinyl proteases, mediate both apoptosis
and inflammation through aspartate-specific cleavage of a wide number of cellular …

1. Apoptosis is an essential process to remove excess, unwanted and harmful cells and
maintain homeostasis. One of the key steps in apoptosis is activation of a group of proteases …

Much of the proteolysis that occurs during apoptosis is directed by caspases, a family of
related cysteinyl proteases. A relatively small number of cellular proteins are targeted by …