Background and Purpose—Anemia after aneurysmal subarachnoid hemorrhage is common
and potentially modifiable. Here, we first evaluate the effect of anemia on neurological …

Background There is uncertainty regarding the effect of anemia and red blood cell
transfusion on functional outcome following acute ischemic stroke. We studied the …

Background and Purpose—The goal of this study was to examine the effects of hypertonic
saline on cerebral blood flow (CBF) in poor-grade patients with subarachnoid hemorrhage …

Each year, approximately 5.5 million people die due to a stroke in the world1 and this
number could continue to rise with an aging popula‐tion. The factors leading to a stroke are …

Background: Hemoglobin tetramers are the major oxygen-carrying molecules within the
blood. We hypothesized that a lower hemoglobin level and its reduced oxygen-carrying …

Liposome‐encapsulated hemoglobin (LEH) is protective early after brain ischemia in rats
and nonhuman primates, but it remains unclear whether the protection persists and confers …

Subarachnoid hemorrhage has a poor prognosis due to the wide array of associated
complications such as vasospasm, early brain injury, cortical spreading depression …

BACKGROUND: Accumulating data suggest that anemia worsens outcomes in critically ill
patients, including those with subarachnoid and intracerebral hemorrhage (ICH). Although …

Subarachnoid haemorrhage (SAH) is a major contributor to the burden of stroke on society.
Treatment options are limited and animal models of SAH do not always mimic key …

During subarachnoid haemorrhage, a blood clot forms in the subarachnoid space releasing
extracellular haemoglobin (Hb), which causes oxidative damage and cell death in …