Three‐dimensional aggregates enhance the therapeutic effects of adipose mesenchymal stem cells for ischemia‐reperfusion induced kidney injury in rats

X Zhao, X Qiu, Y Zhang, S Zhang, X Gu… - Stem cells …, 2016 - Wiley Online Library
It has been shown that administration of adipose derived mesenchymal stem cells
(AdMSCs) enhanced structural and functional recovery of renal ischemia‐reperfusion (IR) …

[HTML][HTML] The effect of adipose-derived mesenchymal stem cells on renal function and histopathology in a rat model of ischemia-reperfusion induced acute kidney injury

S Changizi-Ashtiyani, L Hafazeh… - Iranian Journal of …, 2020 - ncbi.nlm.nih.gov
Objective (s): It has been shown that adipose-derived mesenchymal stem cells (AD-MSC)
have protective effects in acute kidney injury (AKI). This study was conducted to assess the …

Effects of adipose-derived mesenchymal cells on ischemia–reperfusion injury in kidney

K Furuichi, H Shintani, Y Sakai, T Ochiya… - Clinical and …, 2012 - Springer
Background Acute kidney injury (AKI) is a critical condition for kidney and other remote
organs, including the lung. However, available treatments for AKI are limited. In this study …

[HTML][HTML] Therapeutic effect of three-dimensional cultured adipose-derived stem cell-conditioned medium in renal ischemia-reperfusion injury

YS Kim, J Aum, BH Kim, MJ Jang, J Suh… - … Journal of Stem Cells, 2023 - ncbi.nlm.nih.gov
Methods and Results Forty male Sprague‐Dawley rats were randomly divided into four
groups: sham, nephrectomy control, IRI control, ADSC-CM. The ADSC-CM was prepared …

Adipose‐derived mesenchymal stem cells therapy for acute kidney injury induced by ischemia‐reperfusion in a rat model

JB Zhang, XQ Wang, GL Lu… - Clinical and …, 2017 - Wiley Online Library
Acute kidney injury (AKI) represents a group of complicated syndromes with a high mortality
rate. The administration of adipose‐derived mesenchymal stem cells (ADMSC s) has been …

[HTML][HTML] Protective effect of adipose-derived mesenchymal stem cells against acute kidney injury induced by ischemia-reperfusion in Sprague-Dawley rats

H Sheashaa, A Lotfy, F Elhusseini… - Experimental and …, 2016 - spandidos-publications.com
Acute kidney injury (AKI) is a complex clinical condition associated with significant morbidity
and mortality and lacking effective management. Ischemia‑reperfusion injury (IRI) remains …

[HTML][HTML] Comparison of human adipose stromal vascular fraction and adipose-derived mesenchymal stem cells for the attenuation of acute renal ischemia/reperfusion …

L Zhou, Q Song, J Shen, L Xu, Z Xu, R Wu, Y Ge… - Scientific reports, 2017 - nature.com
Stem cells therapy has been suggested as a promising option for the treatment of acute
kidney injury (AKI). This study was performed to compare the abilities of xenogenic …

[HTML][HTML] Cyclosporine-assisted adipose-derived mesenchymal stem cell therapy to mitigate acute kidney ischemia–reperfusion injury

YT Chen, CC Yang, YY Zhen, CG Wallace… - Stem cell research & …, 2013 - Springer
Introduction This study tested the hypothesis that cyclosporine (CsA)-supported syngeneic
adipose-derived mesenchymal stem cell (ADMSC) therapy offered superior attenuation of …

[HTML][HTML] Adipose-derived mesenchymal stem cell protects kidneys against ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction

YT Chen, CK Sun, YC Lin, LT Chang, YL Chen… - Journal of translational …, 2011 - Springer
Background Reactive oxygen species are important mediators exerting toxic effects on
various organs during ischemia-reperfusion (IR) injury. We hypothesized that adipose …

3D spheroid culture enhances survival and therapeutic capacities of MSC s injected into ischemic kidney

Y Xu, T Shi, A Xu, L Zhang - Journal of cellular and molecular …, 2016 - Wiley Online Library
Abstract Three‐dimensional (3D) cell culture has been reported to increase the therapeutic
potentials of mesenchymal stem cells (MSC s). In this study, we aimed to investigate the …