Application of magnetic particle tracking velocimetry to quadrupole magnetic sorting of porcine pancreatic islets

VSK Sajja, TR Hanley, H Gapsis… - Biotechnology and …, 2011 - Wiley Online Library
Magnetic isolation is a promising method for separating and concentrating pancreatic islets
of Langerhans for transplantation in Type 1 diabetes patients. We are developing a …

Engineering quadrupole magnetic flow sorting for the isolation of pancreatic islets

DJ Kennedy, P Todd, S Logan, M Becker… - Journal of Magnetism …, 2007 - Elsevier
Quadrupole magnetic flow sorting (QMS) is being adapted from the separation of
suspensions of single cells (< 15μm) to the isolation of pancreatic islets (150–350μm) for …

Quadrupole magnetic sorting of porcine islets of Langerhans

RM Shenkman, JJ Chalmers, BJ Hering… - … Engineering Part C …, 2009 - liebertpub.com
Islet transplantation is emerging as a treatment option for selected patients with type 1
diabetes. Inconsistent isolation, purification, and recovery of large numbers of high-quality …

Continuous quadrupole magnetic separation of islets during digestion improves purified porcine islet viability

BP Weegman, VS Kumar Sajja… - Journal of Diabetes …, 2016 - Wiley Online Library
Islet transplantation (ITx) is an emerging and promising therapy for patients with
uncontrolled type 1 diabetes. The islet isolation and purification processes require exposure …

High-throughput magnetic flow sorting of human cells selected on the basis of magnetophoretic mobility

LM Reece, L Sanders, D Kennedy… - … , and Analysis of …, 2010 - spiedigitallibrary.org
We have shown the potential of a new method for optimizing the separation of human stem
cell subsets from peripheral blood based on a novel cell labeling technique that leverages …

Microfabricated flow system for magnetic cell and particle separation

G Blankenstein - Scientific and clinical applications of magnetic carriers, 1997 - Springer
A new microchannel-based system for continuous separation of magnetizable particles is
presented, with possible applications in cell and particle separation, immunoassays …

Immunomagnetic isolation of islets from the rat pancreas

P Nandigala, TH Chen, C Yang, WH Hsu… - Biotechnology …, 1997 - Wiley Online Library
Islets were selectively isolated from rat pancreatic digests using magnetic microspheres
coated with anti‐islet monoclonal antibodies. The isolation process was optimized as a …

Optimization of the magnetic field used for immunomagnetic islet purification

JE Davies, RFL James, NJM London… - …, 1995 - journals.lww.com
Purification of islets based on the physical differences in density between exocrine and islet
tissue reduces islet yields and remains one of the factors limiting islet transplantation …

Determination of the magnetic susceptibility of labeled particles by video imaging

S Reddy, LR Moore, L Sun, M Zborowski… - Chemical engineering …, 1996 - Elsevier
Magnetic cell sorting is gaining in popularity as a method to separate and recover viable
cells which differ in functionality, but not in physical characteristics. We are developing a …

Magnetic particle characterization—Magnetophoretic mobility and particle size

C Zhou, ED Boland, PW Todd, TR Hanley - Cytometry Part A, 2016 - Wiley Online Library
Quantitative characterization of magnetic particles is useful for analysis and separation of
labeled cells and magnetic particles. A particle velocimeter is used to directly measure the …