[PDF][PDF] The role of PPARgamma in cardiovascular diseases

M Kvandová, M Majzúnová, I Dovinová - Physiol Res, 2016 - academia.edu
The peroxisome proliferator-activated receptors (PPAR) belong to the nuclear superfamily of
ligand-activated transcription factors. PPARγ acts as a nutrient sensor that regulates several …

PPARs and their effects on the cardiovascular system

A Oyekan - Clinical and Experimental Hypertension, 2011 - Taylor & Francis
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors belonging to the nuclear receptor superfamily that undergo transactivation or …

[HTML][HTML] PPAR-in vascular pathophysiology

N Wang - PPAR research, 2008 - hindawi.com
Peroxisome proliferator-activated receptors belong to the superfamily of ligand-dependent
nuclear receptor transcription factors, which include three subtypes: PPAR-,/, and. PPAR …

The role of PPARδ signaling in the cardiovascular system

Y Ding, KD Yang, Q Yang - Progress in molecular biology and translational …, 2014 - Elsevier
Peroxisome proliferator-activated receptors (PPARα, β/δ, and γ), members of the nuclear
receptor transcription factor superfamily, play important roles in the regulation of metabolism …

[HTML][HTML] Peroxisome proliferator-activated receptors for hypertension

D Usuda, T Kanda - World Journal of Cardiology, 2014 - ncbi.nlm.nih.gov
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors belonging to the nuclear receptor superfamily, which is composed of four members …

The role of PPARs in atherosclerosis

C Duval, G Chinetti, F Trottein, JC Fruchart… - Trends in molecular …, 2002 - cell.com
Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors
that regulate lipid and lipoprotein metabolism, glucose homeostasis and inflammation. The …

Targeting PPARα for the treatment and understanding of cardiovascular diseases

S Li, B Yang, Y Du, Y Lin, J Liu, S Huang… - Cellular Physiology and …, 2019 - karger.com
Three members of the peroxisome proliferator-activated receptor (PPAR) family, PPARα,
PPARγ, and PPARβ/δ, have been investigated widely over the past few decades. Although …

Obesity, peroxisome proliferator-activated receptor, and atherosclerosis in type 2 diabetes

F Blaschke, Y Takata, E Caglayan, RE Law… - … , and vascular biology, 2006 - Am Heart Assoc
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors belonging to the nuclear hormone receptor superfamily. The 3 PPAR isotypes, PPAR …

PPARs as therapeutic targets in cardiovascular disease

M van Bilsen, FA van Nieuwenhoven - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: The role of peroxisome proliferator-activated receptors PPARα,
PPARδ and PPARγ in cardiovascular disease is receiving widespread attention. As ligand …

Significance of peroxisome proliferator-activated receptors in the cardiovascular system in health and disease

E Robinson, DJ Grieve - Pharmacology & therapeutics, 2009 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear
transcription factors that belong to the nuclear receptor superfamily. Three isoforms of PPAR …