Recently, intravenous sedatives and analgesics are being commonly used in children
because of the clinical need for increasing the non-operating room anesthesia and …

Target-controlled infusion (TCI) is a new technique for the administration of intravenous
agents based on real-time pharmacokinetic calculations. Its aim is to control and maintain …

Total intravenous anesthesia (TIVA) is the use of intravenous agents for induction and
maintenance of anesthesia. The most frequently used agent is propofol. Propofol effect is …

Although several hypnotic and opioid drugs are suitable for administration by continuous
intravenous infusion, it is somewhat disquieting to realize just how little we know of their …

Intravenous anaesthesia encompasses intravenous induction and intravenous maintenance
of anaesthesia. Children dislike needles, and therefore there is a tendency to first consider …

Pharmacokinetic pharmacodynamic modeling is an important tool which uses statistical
methodology to provide a better understanding of the relationship between concentration …

Although the inhalational anesthesia is the most popular in children, sometimes intravenous
anesthesia is inevitable when the patients are susceptible for malignant hyperthermia or …

Total intravenous anaesthesia (TIVA) has grown rapidly in popularity over the last two
decades in both adult and paediatric anaesthesia. This rapid increase in popularity is in part …

Modelling and simulation continue to have an important role optimizing drug use during
anaesthesia. Models incorporating influential covariates that better describe drug …

Total intravenous anesthesia is increasingly used in children and in some situations is
mandatory, for example in the child with malignant hyperthermia susceptibility. Propofol is …