[HTML][HTML] Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression
J Martin, K Asjadi, L Hubbard, K Kendall, AF Pardiñas… - Plos one, 2021 - journals.plos.org
Anxiety and depression are common mental health disorders and have a higher prevalence
in females. They are modestly heritable, share genetic liability with other psychiatric …
in females. They are modestly heritable, share genetic liability with other psychiatric …
The contribution of genetic risk to the comorbidity of depression and anxiety: a multi-site electronic health records study
Importance Depression and anxiety are common and highly comorbid, posing a clinical and
public health concern because such comorbidity is associated with poorer outcomes …
public health concern because such comorbidity is associated with poorer outcomes …
Sex differences in anxiety and depression in children with attention deficit hyperactivity disorder: Investigating genetic liability and comorbidity
J Martin, S Shameem Agha, O Eyre… - American Journal of …, 2021 - Wiley Online Library
It is unknown why attention deficit hyperactivity disorder (ADHD) is more common in males,
whereas anxiety and depression show a female population excess. We tested the …
whereas anxiety and depression show a female population excess. We tested the …
Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder
UK Biobank (UKB) is a key contributor in mental health genome-wide association studies
(GWAS) but only~ 31% of participants completed the Mental Health Questionnaire (“MHQ …
(GWAS) but only~ 31% of participants completed the Mental Health Questionnaire (“MHQ …
The genetic contribution to the comorbidity of depression and anxiety: a multi-site electronic health records study of almost 178 000 people
BackgroundDepression and anxiety are common and highly comorbid, and their comorbidity
is associated with poorer outcomes posing clinical and public health concerns. We …
is associated with poorer outcomes posing clinical and public health concerns. We …
[HTML][HTML] Genetic risk profiles for depression and anxiety in adult and elderly cohorts
A Demirkan, BWJH Penninx, K Hek, NR Wray… - Molecular …, 2011 - nature.com
The first generation of genome-wide association studies (GWA studies) for psychiatric
disorders has led to new insights regarding the genetic architecture of these disorders. We …
disorders has led to new insights regarding the genetic architecture of these disorders. We …
Investigating gender-specific effects of familial risk for attention-deficit hyperactivity disorder and other neurodevelopmental disorders in the Swedish population
BackgroundMany psychiatric disorders show gender differences in prevalence. Recent
studies suggest that female patients diagnosed with anxiety and depression carry more …
studies suggest that female patients diagnosed with anxiety and depression carry more …
Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression
Depression and anxiety are highly prevalent and comorbid psychiatric traits that cause
considerable burden worldwide. Previous studies have revealed substantial genetic overlap …
considerable burden worldwide. Previous studies have revealed substantial genetic overlap …
Polygenic risk for severe psychopathology among Europeans is associated with major depressive disorder in Han Chinese women
AC Edwards, AR Docherty, A Moscati… - Psychological …, 2018 - cambridge.org
Background Previous studies have demonstrated that several major psychiatric disorders
are influenced by shared genetic factors. This shared liability may influence clinical features …
are influenced by shared genetic factors. This shared liability may influence clinical features …
Genetic susceptibility for major depressive disorder associates with trajectories of depressive symptoms across childhood and adolescence
Background Early‐onset depression during childhood and adolescence is associated with a
worse course of illness and outcome than adult onset. However, the genetic factors that …
worse course of illness and outcome than adult onset. However, the genetic factors that …