Pulmonary disorders, including asthma, chronic obstructive pulmonary disease (COPD),
pulmonary fibrosis (PF), pulmonary hypertension (PH), and lung cancer, seriously impair the …

Arginine methylation, a vital post-translational modification, plays a pivotal role in numerous
cellular functions such as signal transduction, DNA damage response and repair, regulation …

Protein arginine methyltransferases (PRMTs), enzymes catalyzing the methylation of target
proteins, play an essential role in maintaining functional homeostasis in normal physiology …

ABSTRACT Introduction: Protein arginine methyltransferases (PRMTs) are fundamental
enzymes that specifically modify the arginine residues of versatile substrates in cells. The …

Protein arginine methyltransferases (PRMTs) methylate numerous nuclear and cytoplasmic
substrates and play key roles in various biological processes, including cell death, cell cycle …

Protein arginine methyltransferases (PRMTs) play a crucial role in a variety of biological
processes. Overexpression of PRMTs has been implicated in various human diseases …

Protein arginine methyltransferase 5 (PRMT5) plays critical roles in a wide variety of
biological processes, including tumorigenesis. By screening a library of small chemical …

Protein methylation is a post-translational modification (PTM) that organisms undergo. This
process is considered a part of epigenetics research. In recent years, there has been an …

COPD is defined by tissue remodelling in the smaller airways and emphysema, which is
characterized by airspace enlargement and reduced gas exchange area. Therefore, both for …

Protein arginine methyltransferases (PRMTs) are emerging as attractive therapeutic targets.
PRMTs regulate transcription, splicing, RNA biology, the DNA damage response and cell …