[HTML][HTML] Utilization of leukapheresis and CD4 positive selection in Treg isolation and the ex-vivo expansion for a clinical application in transplantation and autoimmune …
K Gołąb, R Grose, P Trzonkowski, A Wickrema… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Adoptive transfer of T regulatory cells (Tregs) is of great interest as a novel
immunosuppressive therapy in autoimmune disorders and transplantation. Obtaining a …
immunosuppressive therapy in autoimmune disorders and transplantation. Obtaining a …
A rapamycin-based GMP-compatible process for the isolation and expansion of regulatory T cells for clinical trials
H Fraser, N Safinia, N Grageda, S Thirkell… - … therapy Methods & …, 2018 - cell.com
The concept of regulatory T cell (Treg)-based immunotherapy has enormous potential for
facilitating tolerance in autoimmunity and transplantation. Clinical translation of Treg cell …
facilitating tolerance in autoimmunity and transplantation. Clinical translation of Treg cell …
Large-scale isolation of highly pure “untouched” regulatory T cells in a GMP environment for adoptive cell therapy
D Haase, KJ Puan, M Starke, TS Lai… - Journal of …, 2015 - journals.lww.com
Adoptive cell therapy is an emerging treatment strategy for a number of serious diseases.
Regulatory T (Treg) cells represent 1 cell type of particular interest for therapy of …
Regulatory T (Treg) cells represent 1 cell type of particular interest for therapy of …
[PDF][PDF] After moving of regulatory T-cell therapy to the clinic: will we need a new Tregs source
MI Elbadry, AKA Noreldin, HA Hassanein - Hematol Transfus Int J, 2017 - academia.edu
The last few decades, an intense interest has been developed in using regulatory T cells
(Tregs) for immunotherapy by the biomedical community, depending on the facts that Tregs …
(Tregs) for immunotherapy by the biomedical community, depending on the facts that Tregs …
Manufacturing regulatory T cells for adoptive cell therapy in immune diseases: A critical appraisal
Regulatory T cells (Tregs) are a unique subset of lymphocytes that play a vital role in
regulating the immune system by suppressing unwanted immune responses and thus …
regulating the immune system by suppressing unwanted immune responses and thus …
Immunotherapy with regulatory T cells in transplantation
JH Peters, HJPM Koenen, LB Hilbrands… - Immunotherapy, 2009 - Taylor & Francis
Regulatory T cell (Treg)-based immunotherapy is of great interest to induce tolerance in
clinical transplantation settings. In fact, the first clinical trials of Treg infusion after stem cell …
clinical transplantation settings. In fact, the first clinical trials of Treg infusion after stem cell …
Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune …
M Wiesinger, D Stoica, S Roessner, C Lorenz… - Frontiers in …, 2017 - frontiersin.org
In recent years, the exploration of regulatory T cell (Treg)-based cellular therapy has
become an attractive strategy to ameliorate inflammation and autoimmunity in various …
become an attractive strategy to ameliorate inflammation and autoimmunity in various …
Clinical grade multiparametric cell sorting and gene-marking of regulatory T cells
AP Ekwe, R Au, P Zhang, BA McEnroe, ML Tan… - Cytotherapy, 2024 - Elsevier
Background aims Regulatory T cells (Tregs) are the main mediators of peripheral tolerance.
Treg-directed therapy has shown promising results in preclinical studies of diverse …
Treg-directed therapy has shown promising results in preclinical studies of diverse …
Antigen-specific regulatory T cell therapy in autoimmune diseases and transplantation
C Selck, M Dominguez-Villar - Frontiers in immunology, 2021 - frontiersin.org
Regulatory T (Treg) cells are a heterogenous population of immunosuppressive T cells
whose therapeutic potential for the treatment of autoimmune diseases and graft rejection is …
whose therapeutic potential for the treatment of autoimmune diseases and graft rejection is …
Adoptive transfer of allogeneic regulatory T cells into patients with chronic graft-versus-host disease
A Theil, S Tuve, U Oelschlägel, A Maiwald, D Döhler… - Cytotherapy, 2015 - Elsevier
Background aims Mouse models indicate that adoptive transfer of regulatory T cells (Treg)
may suppress graft-versus-host-disease (GvHD) while preserving graft-versus-leukemia …
may suppress graft-versus-host-disease (GvHD) while preserving graft-versus-leukemia …