Since the discovery of regulatory T cells (Tregs) as crucial regulators of immune tolerance
against self-antigens, these cells have become a promising tool for the induction of donor …

Regulatory T cells (Tregs) are a unique subset of lymphocytes that play a vital role in
regulating the immune system by suppressing unwanted immune responses and thus …

Gene editing of living cells is a cornerstone of present-day medical research that has
enabled scientists to address fundamental biologic questions and identify novel strategies to …

Regulatory (Treg) cells are key regulators of inflammation and important for immune
tolerance and homeostasis. A major progress has been made in the identification and …

Regulatory T cells (Tregs) are crucial in maintaining tolerance. Hence, Treg immunotherapy
is an attractive therapeutic option in autoimmune diseases and organ transplantations …

Since their discovery, CD4+ CD25hiFOXP3hi regulatory T cells (Tregs) have been firmly
established as a critical cell type for regulating immune homeostasis through a plethora of …

Forkhead box P3–expressing regulatory T (Treg) cells are essential for self-tolerance, with
an emerging role in tissue repair and regeneration. Their ability to traffic to tissue and …

Abstract The CD4+ FOXP3+ regulatory T (Treg) cells are essential for maintaining immune
homeostasis in healthy individuals. Results from clinical trials of Treg cell-based therapies in …

Regulatory T cells (Treg cells) are a small subset of immune cells that are dedicated to
curbing excessive immune activation and maintaining immune homeostasis. Accordingly …

Autoimmune diseases are caused when immune cells act against self-protein. This
biological self–non-self-discrimination phenomenon is controlled by a distinct group of …