Regulatory T (Treg) cells ensure tolerance against self-antigens, limit excessive
inflammation, and support tissue repair processes. Therefore, Treg cells are currently …

The induction of graft tolerance remains the holy grail of transplantation. This is important as
chronic allograft dysfunction and the side effects of immunosuppression regimens place a …

Endowed with the ability to actively suppress an immune response, regulatory T cells
(Tregs) hold the promise of halting ongoing pathogenic autoimmunity and restoring self …

Regulatory T cells (Tregs) adoptive immunotherapy is emerging as a viable treatment option
for both autoimmune and alloimmune diseases. However, numerous challenges remain …

Human regulatory CD4+ T cells (Tregs) are potent immunosuppressive lymphocytes
responsible for immune tolerance and homeostasis. Since the seminal reports identifying …

Abstract CD4+ FOXP3+ Tregs are currently explored to develop cell therapies against
immune‐mediated disorders, with an increasing focus on antigen receptor‐engineered …

Regulatory T cells (Treg) are currently being evaluated in clinical allotransplantation for
tolerance induction, with proven safety in humans with autoimmune diseases and graft …

Adoptive regulatory T cell therapy: challenges in clinical t... : Current Opinion in Organ
Transplantation Adoptive regulatory T cell therapy: challenges in clinical transplantation : Current …

Regulatory T cells (Tregs) are critical mediators of immune homeostasis and hold significant
promise in the quest for transplantation tolerance. Progress has now reached a critical …

Graft-versus-host disease (GVHD) is the leading cause of morbidity and mortality after
allogeneic hematopoietic stem cell transplantation (allo-HSCT). Immunomodulation using …