Cyclooxygenase inhibitors and cancer: the missing pieces
C Patrono - Journal of Pharmacology and Experimental …, 2023 - ASPET
At 125, aspirin still represents the cornerstone of anti-platelet therapy for the acute treatment
and long-term prevention of atherothrombosis. The development of a selective regimen of …
and long-term prevention of atherothrombosis. The development of a selective regimen of …
[HTML][HTML] Aspirin, cyclooxygenase inhibition and colorectal cancer
C Sostres, CJ Gargallo, A Lanas - World journal of gastrointestinal …, 2014 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common type of cancer worldwide. Screening
measures are far from adequate and not widely available in resource-poor settings. Primary …
measures are far from adequate and not widely available in resource-poor settings. Primary …
Cyclooxygenase inhibitors: drugs for cancer prevention
SJ Shiff, P Shivaprasad, DL Santini - Current opinion in pharmacology, 2003 - Elsevier
Evidence that chronic intake of non-steroidal anti-inflammatory drugs, especially aspirin,
prevents cancer development continues to accumulate. The data are particularly convincing …
prevents cancer development continues to accumulate. The data are particularly convincing …
Cancer prevention: a new era beyond cyclooxygenase-2
B Rigas, K Kashfi - Journal of Pharmacology and Experimental …, 2005 - ASPET
The seminal epidemiological observation that nonsteroidal anti-inflammatory drugs
(NSAIDs) prevent colon and possibly other cancers has spurred novel approaches to cancer …
(NSAIDs) prevent colon and possibly other cancers has spurred novel approaches to cancer …
Pro-inflammatory prostaglandins and progression of colorectal cancer
D Wang, RN DuBois - Cancer letters, 2008 - Elsevier
Chronic inflammation is a risk factor for several gastrointestinal malignancies, including
esophageal, gastric, hepatic, pancreatic and colorectal cancer. It has long been known that …
esophageal, gastric, hepatic, pancreatic and colorectal cancer. It has long been known that …
[HTML][HTML] Similar reductions in the risk of human colon cancer by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors
RE Harris, J Beebe-Donk, GA Alshafie - BMC cancer, 2008 - Springer
Background Epidemiologic and laboratory investigations suggest that aspirin and other
nonsteroidal anti-inflammatory drugs (NSAIDs) have chemopreventive effects against colon …
nonsteroidal anti-inflammatory drugs (NSAIDs) have chemopreventive effects against colon …
Current concepts in colorectal cancer prevention with cyclooxygenase inhibitors
GS Ranger - Anticancer research, 2014 - ar.iiarjournals.org
Colorectal cancer is one of the commonest malignancies worldwide. Recently, there has
been much speculation regarding the role of cyclooxygenase-2 (COX-2) suppression in …
been much speculation regarding the role of cyclooxygenase-2 (COX-2) suppression in …
Aspirin in the chemoprevention of colorectal neoplasia: an overview
Considerable evidence supports the effectiveness of aspirin for chemoprevention of
colorectal cancer (CRC) in addition to its well-established benefits in the prevention of …
colorectal cancer (CRC) in addition to its well-established benefits in the prevention of …
cyclooxygenase–a target for colon cancer prevention
RN Dubois - Alimentary Pharmacology & Therapeutics, 2000 - Wiley Online Library
Use of nonsteroidal anti‐inflammatory drugs such as aspirin, which are known to inhibit
cyclooxygenase activity, reduces the relative risk of colorectal cancer in humans by 40–50 …
cyclooxygenase activity, reduces the relative risk of colorectal cancer in humans by 40–50 …
Cyclooxygenase as a target for colorectal cancer chemoprevention
L Moreira, A Castells - Current drug targets, 2011 - ingentaconnect.com
Colorectal cancer (CRC) is one of the most common neoplasia in Western countries and the
second leading cause of cancer-related death. The vast majority of cases belong to sporadic …
second leading cause of cancer-related death. The vast majority of cases belong to sporadic …