Anti-Hypertensive Drugs Moderate the Relationship of Blood Pressure with Alzheimer's Pathologies and Neurodegenerative Markers in Non-Demented Hypertensive …

Y Guo, CC Tan, MS Tan, L Tan, W Xu… - The Journal of …, 2024 - Springer
Background We aimed to explore whether the relationships of blood pressures (BPs) with
Alzheimer's disease (AD) endophenotypes varied by usage of antihypertensive drugs …

Association between chronic blood pressure changes and development of Alzheimer's disease

CA Feldstein - Journal of Alzheimer's Disease, 2012 - content.iospress.com
Epidemiological studies suggest an association between chronic blood pressure (BP)
changes and Alzheimer's disease (AD). In particular, there is growing evidence that …

Pathophysiological association of alzheimer's disease and hypertension: A clinical concern for elderly population

Q Yao, K Jiang, F Lin, T Zhu, NH Khan… - Clinical Interventions in …, 2023 - Taylor & Francis
Abstract Alzheimer's disease (AD), the most common cause of dementia and the fifth leading
cause of death in the adult population has a complex pathophysiological link with …

Blood Pressure, Antihypertensive Use, and Late-Life Alzheimer and Non-Alzheimer Dementia Risk: An Individual Participant Data Meta-Analysis

MJ Lennon, DM Lipnicki, BCP Lam, JD Crawford… - Neurology, 2024 - neurology.org
Background and Objectives Previous randomized controlled trials and longitudinal studies
have indicated that ongoing antihypertensive use in late life reduces all-cause dementia …

[HTML][HTML] Effects of Hypertension on Alzheimer's Disease: Updates in Pathophysiological and Neuroimaging Findings

SC Yan, L Liu, GL Fang, ST Weng, JJ Wang… - Journal of Integrative …, 2024 - imrpress.com
Alzheimer's disease (AD) is recognized as the leading cause of dementia, imposing a
significant economic toll on society. Despite the emergence of novel therapeutic approaches …

Shedding Light on the Effects of Blood Pressure on Cognitive Decline and Dementia Risk by Way of Neurobiological Evidence

FF de Oliveira - Journal of Alzheimer's Disease, 2024 - content.iospress.com
Midlife cerebrovascular risk factors increase risk of late life cognitive impairment and
dementia, while their presence in patients with dementia may lead to cognitive improvement …

Self-Reported Late-Life Hypertension Is Associated with a Healthy Cognitive Status and Reduced Alzheimer's Disease Pathology Burden

AC Robinson, T Bin Rizwan… - Journal of …, 2024 - content.iospress.com
Background: While mid-life hypertension represents a risk factor for the development of
Alzheimer's disease (AD), the risk after the age of 65 is less certain. Establishing …

Hypertension & dementia: Pathophysiology & potential utility of antihypertensives in reducing disease burden

M Lyon, JL Fullerton, S Kennedy, LM Work - Pharmacology & Therapeutics, 2023 - Elsevier
Dementia is a common cause of disability and dependency among the elderly due to its
progressive neurodegenerative nature. As there is currently no curative therapy, it is of major …

Antihypertensive drugs decrease risk of Alzheimer disease: Ginkgo Evaluation of Memory Study

S Yasar, J Xia, W Yao, CD Furberg, QL Xue… - Neurology, 2013 - AAN Enterprises
Objectives: The aim of this study was to determine whether use of diuretics, angiotensin-1
receptor blockers (ARB), angiotensin-converting enzyme inhibitors (ACE-I), calcium channel …

Walking the cognitive “minefield” between high and low blood pressure

S Kennelly, O Collins - Journal of Alzheimer's Disease, 2012 - content.iospress.com
Vascular risk factors are implicated in the pathogenesis of Alzheimer's disease (AD). There
is an age-dependent relationship between blood pressure and the risk of AD. Given the …