Accumulating evidence shows that hallmarks of cancer include:“genetic and epigenetic
alterations leading to inactivation of cancer suppressors, overexpression of oncogenes …

Carcinogenesis is a complex and multistep process that involves the accumulation of
successive transformational events driven by genetic mutations and epigenetic alterations …

Cancer is a disease caused by a series of genetic and epigenetic alterations. Therefore,
agents targeting the genetic and/or epigenetic machinery offer potential for the development …

Epigenetic mechanisms are essential for normal development and maintenance of adult life.
Disruption of epigenetic processes results in deregulated gene expression and leads to life …

For centuries, plants have been serving as sources of potential therapeutic agents. In recent
years, there has been a growing interest in investigating the effects of plant-derived …

Epigenetic mechanisms control gene expression during normal development and their
aberrant regulation may lead to human diseases including cancer. Natural phytochemicals …

Cancer is the main cause of death in developing countries. Its development requires
multiple steps in which the occurrence of certain events determines the state transition from …

Owing to the technological advancements, including next generation sequencing, the
significance of deregulated epigenetic mechanisms in cancer initiation, progression and …

This review provides a brief overview of the basic principles of epigenetic gene regulation
and then focuses on recent development of epigenetic drugs for cancer treatment and …

Background: Cancer-induced mortality is increasingly prevalent globally, which skyrocketed
the necessity to discover new/novel, safe and effective anticancer drugs. Cancer is …