Potential anti-SARS-CoV-2 therapeutics that target the post-entry stages of the viral life cycle: A comprehensive review

RA Al-Horani, S Kar - Viruses, 2020 - mdpi.com
The coronavirus disease-2019 (COVID-19) pandemic continues to challenge health care
systems around the world. Scientists and pharmaceutical companies have promptly …

Potential anti-COVID-19 therapeutics that block the early stage of the viral life cycle: structures, mechanisms, and clinical trials

RA Al-Horani, S Kar, KF Aliter - International Journal of Molecular …, 2020 - mdpi.com
The ongoing pandemic of coronavirus disease-2019 (COVID-19) is being caused by severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The disease continues to present …

Approaches and advances in the development of potential therapeutic targets and antiviral agents for the management of SARS-CoV-2 infection

G Krishna, VS Pillai, MV Veettil - European Journal of Pharmacology, 2020 - Elsevier
Virus onslaughts continue to spread fear and cause rampage across the world every now
and then. The twenty first century is yet again witnessing a gross global pandemic …

COVID-19 therapeutic options under investigation

M Kaddoura, M AlIbrahim, G Hijazi… - Frontiers in …, 2020 - frontiersin.org
Since its emergence in China in December 2019, COVID-19 has quickly spread around the
globe causing a pandemic. Vaccination or the development of herd immunity seems the only …

After the hurricane: Anti-COVID-19 drugs development, molecular mechanisms of action and future perspectives

HO Khalifa, YM Al Ramahi - International Journal of Molecular Sciences, 2024 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a new coronavirus in
the Coronaviridae family. The COVID-19 pandemic, caused by SARS-CoV-2, has …

Tackling COVID‐19 using remdesivir and favipiravir as therapeutic options

O Sreekanth Reddy, WF Lai - ChemBioChem, 2021 - Wiley Online Library
The human world is currently influenced largely by the outbreak of pandemic COVID‐19. At
this moment, most researchers focus on developing treatment strategies and measures to …

Drugs targeting various stages of the SARS-CoV-2 life cycle: Exploring promising drugs for the treatment of Covid-19

R Poduri, G Joshi, G Jagadeesh - Cellular signalling, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense,
single-stranded RNA virus that causes the potentially lethal Covid-19 respiratory tract …

Mechanism of action of small-molecule agents in ongoing clinical trials for SARS-CoV-2: a review

L Zhao, S Li, W Zhong - Frontiers in Pharmacology, 2022 - frontiersin.org
Since the first reports from December 2019, COVID-19 caused an overwhelming global
pandemic that has affected 223 countries, seriously endangering public health and creating …

Potential inhibitors of SARS-CoV-2: recent advances

G Jamalipour Soufi, S Iravani - Journal of Drug Targeting, 2021 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appeared in 2019 and is
the causative agent of the new pandemic viral disease COVID-19. The outbreak of COVID …

COVID-19: drug targets and potential treatments

C Gil, T Ginex, I Maestro, V Nozal… - Journal of medicinal …, 2020 - ACS Publications
Currently, humans are immersed in a pandemic caused by the emerging severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), which threatens public health …