How mechanical forces change the human endometrium during the menstrual cycle in preparation for embryo implantation

AK Sternberg, VU Buck, I Classen-Linke, RE Leube - Cells, 2021 - mdpi.com
The human endometrium is characterized by exceptional plasticity, as evidenced by rapid
growth and differentiation during the menstrual cycle and fast tissue remodeling during early …

Tissue stiffness at the human maternal–fetal interface

Y Abbas, A Carnicer-Lombarte, L Gardner… - Human …, 2019 - academic.oup.com
STUDY QUESTION What is the stiffness (elastic modulus) of human nonpregnant secretory
phase endometrium, first trimester decidua, and placenta? SUMMARY ANSWER The …

[HTML][HTML] Morphophysical dynamics of human endometrial cells during decidualization

B Pan-Castillo, SA Gazze, S Thomas, C Lucas… - … , Biology and Medicine, 2018 - Elsevier
During decidualization, human mesenchymal-like endometrial stromal cells undergo well
characterized cellular and molecular transformations in preparation for accepting a …

Mechanical signaling in reproductive tissues: mechanisms and importance

S Jorge, S Chang, JJ Barzilai, P Leppert… - Reproductive …, 2014 - journals.sagepub.com
The organs of the female reproductive system are among the most dynamic tissues in the
human body, undergoing repeated cycles of growth and involution from puberty through …

Microphysiological modeling of the human endometrium

H Campo, A Murphy, S Yildiz, T Woodruff… - … Engineering Part A, 2020 - liebertpub.com
Since the beginning of clinical medicine, the human uterus has held the fascination of
clinicians and researchers, given its critical role in the reproduction of our species. The …

Biomechanics of the human uterus

KM Myers, D Elad - Wiley Interdisciplinary Reviews: Systems …, 2017 - Wiley Online Library
The appropriate biomechanical function of the uterus is required for the execution of human
reproduction. These functions range from aiding the transport of the embryo to the …

In vitro studies on endometrial adhesiveness for trophoblast: cellular dynamics in uterine epithelial cells

M Thie, HW Denker - Cells Tissues Organs, 2002 - karger.com
Initiation of embryo implantation involves adhesion of trophoblast cells to the epithelial lining
of the endometrium. The mechanisms regulating the adhesive properties of the uterine …

Mechanical stretch upregulates IGFBP-1 secretion from decidualized endometrial stromal cells

M Harada, Y Osuga, Y Takemura… - American Journal …, 2006 - journals.physiology.org
Decidualization is an essential process of endometrial differentiation for embryo
implantation and maintenance of pregnancy. Recently, uterine movement-induced …

Characterization of mechanical signature of eutopic endometrial stromal cells of endometriosis patients

A Altayyeb, E Othman, M Khashbah, A Esmaeel… - Reproductive …, 2020 - Springer
Abstract Endometriosis affects 5–10% of women in reproductive age and causes pelvic pain
and subfertility. Exact etiology of the disease is unknown. Here, we present a microfluidic …

Effects of matrix stiffness on epithelial to mesenchymal transition-like processes of endometrial epithelial cells: Implications for the pathogenesis of endometriosis

S Matsuzaki, C Darcha, JL Pouly, M Canis - Scientific reports, 2017 - nature.com
Endometriosis is defined as the presence of endometrial glands and stroma within
extrauterine sites. Our previous study revealed an epithelial to mesenchymal transition …