Real-world intensive safety monitoring of biosimilars rituximab and trastuzumab in a Portuguese oncology hospital

D Mendes, J Abrantes, G Rigueiro… - Journal of Oncology …, 2021 - journals.sagepub.com
Purpose The aim of this study was to assess the safety profiles of two biosimilar medicines
(rituximab and trastuzumab) in the treatment of cancer patients within a Portuguese …

Safety and efficacy comparisons of rituximab biosimilars to the reference product in patients with cancer: a systematic meta‐analysis review

NK Song, H Musa, M Soriano, M Batger… - Journal of Pharmacy …, 2022 - Wiley Online Library
Aim To compare the efficacy and safety of rituximab biosimilars to reference rituximab in
patients with cancer. Data Sources A systematic review and meta‐analysis was conducted …

Rituximab Reference vs Biosimilar Utilization for Oncology vs Nononcology Indications.

BA Labdi, RA Elbeshbeshy, M Winkler… - American Journal of …, 2023 - search.ebscohost.com
OBJECTIVES: Limited data exist on the adoption of rituximab biosimilars vs the reference
product by indication. Available data from real-world studies comparing rituximab biosimilar …

Post‐marketing safety of antineoplasic monoclonal antibodies: rituximab and trastuzumab

V González, E Salgueiro, FJ Jimeno… - … and drug safety, 2008 - Wiley Online Library
Purpose The aim of this study was to analyse the suspected adverse reactions associated
with rituximab or trastuzumab reported to the Spanish Pharmacovigilance System. Methods …

[HTML][HTML] Comparative safety profiles of oncology biosimilars vs. originators in Europe: an analysis of the EudraVigilance Database

V Nikitina, G Santi Laurini, N Montanaro, D Motola - Cancers, 2023 - mdpi.com
Simple Summary Nowadays, biosimilar drugs are numerous and widely used in many
clinical fields, including oncology. However, skepticism remains towards these products …

Real-world use and acceptance of biosimilar monoclonal antibodies of rituximab in oncology practice in the USA

A Shelbaya, JM Kelton, J Thompson, JMJ Alvir… - Future …, 2021 - Future Medicine
Aim: To describe treatment patterns and patient and provider characteristics associated with
the recently introduced biosimilar rituximab-pvvr. Methods: This retrospective analysis …

[HTML][HTML] Severe Hypersensitivity Reactions at Biosimilar versus Originator Rituximab Treatment Initiation, Switch and Over Time: A Cohort Study on the French …

H Jourdain, L Hoisnard, E Sbidian, M Zureik - BioDrugs, 2023 - Springer
Background Biosimilar products of rituximab came to market in 2017. French
pharmacovigilance centers have highlighted an excess of case reports of severe …

Comparison of adverse event profiles of rituximab, rituximab hycela and rituximab biosimilars: a real-world pharmacovigilance database analysis

D Keerty, A Ananthaneni, P Ramadas, SR Master - Blood, 2022 - ashpublications.org
Background: Rituximab is a chimeric monoclonal antibody which targets CD20 and is used
for treatment of CD20 associated oncologic/hematologic conditions. Murine-derived variable …

[HTML][HTML] Understanding the role of comparative clinical studies in the development of oncology biosimilars

J Stebbing, PN Mainwaring, G Curigliano… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
Biosimilars have the potential to broaden patient access to biologics and provide cost
savings for health care systems. During the development of a biosimilar, data that directly …

The in-use stability of the rituximab biosimilar Rixathon®/Riximyo® upon preparation for intravenous infusion

WC Lamanna, K Heller, D Schneider… - Journal of Oncology …, 2019 - journals.sagepub.com
Purpose The purpose of this study was to evaluate the in-use physicochemical and
biological stability of the Sandoz rituximab biosimilar, marketed under the trade names …