Effective asymmetry in gap junctional intercellular communication between populations of human normal lung fibroblasts and lung carcinoma cells
ZQ Zhang, Y Hu, BJ Wang, ZX Lin, CCG Naus… - …, 2004 - academic.oup.com
The dysfunction of homologous and/or heterologous gap junctional intercellular
communication (GJIC) has been implicated in tumorigenesis of many kinds of cells. Here we …
communication (GJIC) has been implicated in tumorigenesis of many kinds of cells. Here we …
Role of gap junctions in lung neoplasia
RJ Ruch, K Cesen-Cummings… - Experimental lung …, 1998 - Taylor & Francis
Reduced gap junctional intercellular communication (GJIC) has been noted in many types of
neoplastic cells and may contribute to the neoplastic phenotype. This study assessed GJIC …
neoplastic cells and may contribute to the neoplastic phenotype. This study assessed GJIC …
Gap junctional intercellular communication in mouse lung epithelial cell lines: effects of cell transformation and tumor promoters
R Chaudhuri, K Sigler, E Dupont, JE Trosko… - Cancer letters, 1993 - Elsevier
Gap junctional intercellular communication (GJIC) is reduced by neoplastic transformation
and treatment with tumor promoters in many types of cells but few data exist for the lung …
and treatment with tumor promoters in many types of cells but few data exist for the lung …
Frequent reduction of gap junctional intercellular communication and connexin43 expression in human and mouse lung carcinoma cells.
K Cesen-Cummings, MJ Fernstrom… - …, 1998 - academic.oup.com
The reduced gap junctional intercellular communication (GJIC) and gap junction protein
(connexin) expression that have been noted in many neoplastic cell types may contribute to …
(connexin) expression that have been noted in many neoplastic cell types may contribute to …
Inhibition of intrinsic gap‐junction intercellular communication and enhancement of tumorigenicity of the rat bladder carcinoma cell line BC31 by a dominant‐negative …
VA Krutovskikh, H Yamasaki, H Tsuda… - … in cooperation with …, 1998 - Wiley Online Library
The tumor‐suppressive property of the connexin gap‐junction proteins was postulated from
the fact that their function of cell coupling is impaired in most cancer cells. However, in …
the fact that their function of cell coupling is impaired in most cancer cells. However, in …
Connexin expression in mouse lung tumor
N Udaka, Y Miyagi, T Ito - Cancer letters, 2007 - Elsevier
Gap junction intercellular communication (GJIC) is considered to play roles in regulation of
homeostasis, development and differentiation of many tissues. In the present study, using …
homeostasis, development and differentiation of many tissues. In the present study, using …
Suppression of tumorigenicity of human lung carcinoma cells after transfection with connexin43.
ZQ Zhang, W Zhang, NQ Wang… - …, 1998 - academic.oup.com
The human lung carcinoma cell line PG is defective in gap junctional intercellular
communication (GJIC). Connexin43 (Cx43) mRNA, which is expressed in normal human …
communication (GJIC). Connexin43 (Cx43) mRNA, which is expressed in normal human …
Gap-junctional communication alterations at various regulatory levels of connexin expression and function during animal and human carcinogenesis
The loss of homeostasis which characterizes tumor growth is probably the result of a
deregulated intercellular communication capacity of the cancer cells. The deregulation of …
deregulated intercellular communication capacity of the cancer cells. The deregulation of …
Gap junctional communication in cultured human lung carcinoma cells
E Tomai, HL Brownell, TV Tufescu, K Reid… - Lung Cancer, 1999 - Elsevier
Animal tumor models have demonstrated a close correlation between gap junctional,
intercellular communication (GJIC) and tumor metastasis. To examine GJIC levels in human …
intercellular communication (GJIC) and tumor metastasis. To examine GJIC levels in human …
Proteomic analysis of a neoplastic mouse lung epithelial cell line whose tumorigenicity has been abrogated by transfection with the gap junction structural gene for …
KA Peebles, MW Duncan, RJ Ruch… - …, 2003 - academic.oup.com
In order to examine how tumorigenicity is abrogated by gap junctional intercellular
communication (GJIC), protein expression was analyzed in four related mouse lung …
communication (GJIC), protein expression was analyzed in four related mouse lung …