Abstract Progesterone Receptor Membrane Component 1 (PGRMC1) is a candidate
oncogene with a prominent involvement in the pathogenesis of diverse cancers (ovarian …

Progesterone Receptor Membrane Component 1 (PGRMC1/Sigma-2 receptor) is located on
chromosome Xq21 and encodes a haem-containing protein that interacts with epidermal …

Background Increased expression of the progesterone receptor membrane component 1
(PGRMC1) has been linked to multiple cancers, including breast cancer. Despite being a …

In non-small-cell lung cancer, mutation of epidermal growth factor receptor (EGFR)
stimulates cell proliferation and survival. EGFR tyrosine kinase inhibitors (EGFR-TKIs) such …

Cancer is one of the leading causes of death in America, and there is an urgent need for
new therapeutic approaches. The progesterone receptor membrane component 1 …

Aims The most frequent cancers among women worldwide. The mortality of cervical cancer
has declined significantly primarily due to the widespread use of Pap smear tests as a …

Progesterone receptor membrane component 1 (PGRMC1) is a trans-membrane
evolutionarily conserved protein with a cytochrome b5 like heme/steroid binding domain …

Background: The G protein-coupled oestrogen receptor (GPER) 1 mediates non-genomic
oestrogen-related signalling and plays an important role in the regulation of cell growth and …

Abstract Background Glypican 3 (GPC3) is a heparin sulphate proteoglycan whose
expression is associated with several malignancies. However, its expression in non-small …

Cancer metastasis is a common cause of failure in cancer therapy. However, over 60% of
oral cancer patients present with advanced stage disease, and the five‐year survival rates of …