Transcriptomic analysis reveals the relationship of melanization to growth and resistance to gamma radiation in Cryptococcus neoformans

Z Schultzhaus, A Chen, S Kim, I Shuryak… - Environmental …, 2019 - Wiley Online Library
The pathogenic fungus Cryptococcus neoformans produces melanin within its cell wall for
infection and resistance against external stresses such as exposure to UV, temperature …

Bacterial pigments: A colorful palette reservoir for biotechnological applications

VT Orlandi, E Martegani, C Giaroni… - Biotechnology and …, 2022 - Wiley Online Library
Synthetic derivatives are currently used instead of pigments in many applicative fields, from
food to feed, from pharmaceutical to diagnostic, from agronomy to industry. Progress in …

Histoplasma capsulatum Synthesizes Melanin-Like Pigments In Vitro and during Mammalian Infection

JD Nosanchuk, BL Gómez, S Youngchim… - Infection and …, 2002 - Am Soc Microbiol
Melanin is made by several important pathogenic fungi and has been implicated in the
pathogenesis of a number of fungal infections. This study investigated whether the thermally …

The melanization road more traveled by: Precursor substrate effects on melanin synthesis in cell-free and fungal cell systems

S Chatterjee, R Prados-Rosales, S Tan… - Journal of Biological …, 2018 - ASBMB
Natural brown–black eumelanin pigments confer structural coloration in animals and
potently block ionizing radiation and antifungal drugs. These functions also make them …

Functions of fungal melanin beyond virulence

RJB Cordero, A Casadevall - Fungal Biology Reviews, 2017 - Elsevier
Melanins are ancient biological pigments found in all kingdoms of life. In fungi, their role in
microbial pathogenesis is well established; however, these complex biomolecules also …

Melanization of Cryptococcus neoformans Affects Lung Inflammatory Responses during Cryptococcal Infection

AJ Mednick, JD Nosanchuk… - Infection and immunity, 2005 - Am Soc Microbiol
The production of melanin pigments is associated with virulence for many microbes. Melanin
is believed to contribute to microbial virulence by protecting microbial cells from oxidative …

The role of melanin in the biology and ecology of nematophagous Fungi

DF Freitas, IM da Rocha, O Vieira-da-Motta… - Journal of Chemical …, 2021 - Springer
Melanin is a heteropolymer formed by the polymerization of phenolic and indolic
compounds. It occurs in organisms across all biological kingdoms and has a range different …

Cryptococcus neoformans/Cryptococcus gattii species complex melanized by epinephrine: Increased yeast survival after amphotericin B exposure

RSN Brilhante, MG da Rocha, JS de Oliveira… - Microbial …, 2020 - Elsevier
Cryptococcus neoformans/Cryptococcus gattii complex species are etiological agents of
cryptococcosis, a systemic mycosis that cause respiratory infection and …

Investigation of the influence of pH and temperature on melanization and survival under oxidative stress in Cryptococcus neoformans

D Kumari, N Sachivkina, R Pasrija - Archives of Microbiology, 2024 - Springer
Cryptococcus neoformans is an opportunistic pathogenic fungus that produces melanin
during infection, an important virulence factor in Cryptococcal infections that enhances the …

Degradation of melanin or inhibition of its synthesis: are these a significant approach as a biological control of phytopathogenic fungi?

MJ Butler, RB Gardiner, AW Day - Biological Control, 2005 - Elsevier
Many fungal plant pathogens produce melanins that play direct or indirect roles in the
infection process. Destruction of the melanin or inhibition of its synthesis by biological …