Carboxylesterase (CES) is important for detoxification of a wide range of drugs and
xenobiotics and catalyzes cholesterol and fatty acid metabolism. Cynomolgus macaques are …

Carboxylesterase (CES) is important for the detoxification of a wide range of drugs and
xenobiotics. In this study, the hepatic level of CES2 mRNA was examined in cynomolgus …

The carboxylesterases (CESs) are a family of serine hydrolases that hydrolyze compounds
containing an ester, amide, or thioester. In humans, two dominant forms, CES1 and CES2 …

Background Carboxylesterase (CES) is predominantly responsible for the detoxification of a
wide range of drugs and narcotics, and catalyze several reactions in cholesterol and fatty …

Carboxylesterases belong to Phase I group of drug metabolizing enzymes. They hydrolyze a
variety of drug esters, amides, carbamates and similar structures. There are five …

Human carboxylesterase (CES) 1 and CES2 are members of the serine hydrolase
superfamily, and both exhibit broad substrate specificity and are involved in xenobiotic and …

In contrast to a single human carboxylesterase 2 (CES2) isozyme (hCE2), three CES2
genes have been identified in cynomolgus monkeys: mfCES2A, mfCES2B, and mfCES2C …

At least five families of mammalian carboxylesterases (CES) catalyse the hydrolysis or
transesterification of a wide range of drugs and xenobiotics and may also participate in fatty …

抄録 Liver microsomal carboxylesterases (CES) function in the hydrolysis of a wide variety of
endogenous and xenobiotic compounds, and play an important role in drug and lipid …

Carboxylesterases (CES) metabolize esters. Two CES isoforms are expressed in human
liver (CES1 and CES2) and liver extracts are used in reaction phenotyping studies to discern …