Combination of UHPLC/Q-TOF-MS, NMR spectroscopy, and ECD calculation for screening and identification of reactive metabolites of gentiopicroside in humans

H Han, AZ Xiong, CY He, Q Liu, L Yang… - Analytical and …, 2014 - Springer
The metabolic investigation of natural products is a great challenge because of
unpredictable metabolic pathways, little knowledge on metabolic effects, and lack of …

[HTML][HTML] Astragalin: A food-origin flavonoid with therapeutic effect for multiple diseases

J Chen, K Zhong, S Qin, Y Jing, S Liu, D Li… - Frontiers in …, 2023 - frontiersin.org
Naturally occurring flavonoids have long been utilized as essential templates for the
development of novel drugs and as critical ingredients for functional foods. Astragalin (AG) is …

Galangin's potential as a functional food ingredient

KK Mak, JJ Tan, P Marappan, MK Balijepalli… - Journal of Functional …, 2018 - Elsevier
Foods that show positive effects on health beyond basic nutrition are called functional foods
of which familiar examples are propolis and Alpinia officinarum. Galangin (3, 4, 5 …

[HTML][HTML] Biflavonoids: Important Contributions to the Health Benefits of Ginkgo (Ginkgo biloba L.)

D Šamec, E Karalija, S Dahija, STS Hassan - Plants, 2022 - mdpi.com
Ginkgo (Ginkgo biloba L.) is one of the most distinctive plants, characterized by excellent
resistance to various environmental conditions. It is used as an ornamental plant and is …

Simultaneous quantification of three isoflavonoid glycosides in rabbit plasma after oral administration of Astragalus mongholicus extract by high-performance liquid …

X Zhang, YG Sun, MC Cheng, YQ Wang, HB Xiao… - Analytica Chimica …, 2007 - Elsevier
A selective and sensitive liquid chromatography coupled with triple stage quadruple tandem
mass spectrometry (HPLC/TSQ-MS/MS) was developed and validated for simultaneous …

Isoflavones derived from plant raw materials: Bioavailability, anti-cancer, anti-aging potentials, and microbiome modulation

SA Aboushanab, SM Khedr, IF Gette… - Critical Reviews in …, 2022 - Taylor & Francis
Isoflavones are secondary metabolites that represent the most abundant category of plant
polyphenols. Dietary soy, kudzu, and red clover contain primarily genistein, daidzein …

[HTML][HTML] An update on the effects of glyceollins on human health: possible anticancer effects and underlying mechanisms

TH Pham, S Lecomte, T Efstathiou, F Ferriere, F Pakdel - Nutrients, 2019 - mdpi.com
Biologically active plant-based compounds, commonly referred to as phytochemicals, can
influence the expression and function of various receptors and transcription factors or …

[PDF][PDF] Pharmacological Aspects of a Bioactive Compound Arbutin: A Comprehensive Review

M Bhalla, R Mittal, M Kumar… - Biointerface Res. Appl …, 2022 - academia.edu
Over the past few decades, researchers emphasized herbal medicines as an alternative
therapeutic approach due to the high success rate of developing a new drug from a natural …

[HTML][HTML] Biological Activity and Metabolomics of Griffonia simplicifolia Seeds Extracted with Different Methodologies

G Mannino, G Serio, R Gaglio, ME Maffei, L Settanni… - Antioxidants, 2023 - mdpi.com
Griffonia simplicifolia, a tropical plant endemic to West Africa, is highly regarded for its
significant pharmacological potential. The objective of this study was to evaluate the …

Molecular mechanisms underlying the absorption of aglycone and glycosidic flavonoids in a Caco-2 BBe1 cell model

H Zhang, YI Hassan, R Liu, L Mats, C Yang, C Liu… - ACS …, 2020 - ACS Publications
The mechanisms of cellular absorption and transport underlying the differences between
flavonoid aglycones and glycosides and the effect of the structural feature are not well …