Abstract Analysis of chimerism in blood post‐HCT using STR‐PCR is routinely applied in
parallel with quantification of MRD to predict relapse of leukemia. RQ‐PCR chimerism is 10 …

Detection of increasing mixed chimerism (IMC) using standard PCR correlates with relapse
after allo-SCT for acute leukemias (ALs). Quantitative real-time PCR of insertion/deletion …

Increasing mixed chimerism (MC) after allogeneic stem cell transplantation (SCT) has been
associated with a high risk of relapse in acute leukemia. We evaluated a new method for …

The monitoring of chimerism by PCR has become a routine diagnostic approach in patients
after allogeneic bone marrow or peripheral blood stem cell transplantation. Nevertheless, a …

Posttransplant leukemia detection before overt relapse is key to the success of
immunotherapeutic interventions, as they are more efficient when leukemia burden is low …

Allogeneic hematopoietic stem cell transplantation is required as rescue therapy in about
20% of pediatric patients with acute lymphoblastic leukemia. However, the relapse rates are …

In patients receiving allogeneic stem cell transplantation (SCT) for treatment of malignant
hematologic disorders, residual leukemia can be assessed by different methodologic …

Chimerism and clinical outcome data from 244 hematopoietic stem cell transplants in 218
children were retrospectively analyzed to assess their relevance for the detection of graft …

OBJECTIVE: Chimerism is well-established for surveillance of acute myeloid leukemia
(AML) patients after allogeneic hematopoietic stem cell transplantation (HSCT), but …

Despite better results with hematopoietic stem cell transplantation (HSCT) over the years,
high rates of relapse, which in acute leukemia can reach 30-70% of cases, remain a major …