Embryo quality is a crucial factor affecting live birth outcomes. However, an accurate
diagnostic for embryo quality remains elusive in the in vitro fertilization clinic. Determining …

Assisted reproductive technologies seek to improve the success rate of pregnancies.
Morphology scoring is a common approach to evaluate oocyte and embryo viability prior to …

Digital holographic microscopy (DHM) has been applied extensively to in vitro studies of
different living cells. In this paper, we present a novel application of an off-axis DHM system …

Embryonic stem cells are very important for the development of cell-based therapeutic
strategies. Since stem cell colonies are nonpigmented and relatively transparent, they do not …

Multi-wavelength digital holographic microscopy (MWDHM) provides indirect measurements
of the refractive index for non-dispersive samples. Successive-shot MWDHM is not …

Morphology and motility are essential criteria for assessing sperm viability. However, the
human sperm head is small (∼ 3–4 μm) and requires a relatively high-magnification …

Biological cells are usually transparent with a small refractive index gradient. Digital
holographic interferometry can be used in the measurement of biological cells. We propose …

Although the biochemical changes that occur during cell differentiation are well-known, less
known is that there are significant, cell-wide physical changes that also occur …

The understanding of biological reactions and evaluation of the significance for living cells
strongly depends on the ability to visualize and quantify these processes. Digital …

Exposure to laser light alters cell culture examination via optical microscopic imaging
techniques based on label-free coherent digital holography. To mitigate this detrimental …