Reproducible large-scale isolation of exosomes from adipose tissue-derived mesenchymal stem/stromal cells and their application in acute kidney injury
Acute kidney injury (AKI) is a fatal medical episode caused by sudden kidney damage or
failure, leading to the death of patients within a few hours or days. Previous studies …
failure, leading to the death of patients within a few hours or days. Previous studies …
Mesenchymal stem cells-derived exosomes ameliorate ischemia/reperfusion induced acute kidney injury in a porcine model
J Huang, H Cao, B Cui, X Ma, L Gao, C Yu… - Frontiers in cell and …, 2022 - frontiersin.org
Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …
Three-dimensional culture of MSCs produces exosomes with improved yield and enhanced therapeutic efficacy for cisplatin-induced acute kidney injury
J Cao, B Wang, T Tang, L Lv, Z Ding, Z Li, R Hu… - Stem cell research & …, 2020 - Springer
Background Exosomes derived from mesenchymal stem cells (MSC-exos) have been
demonstrated with great potential in the treatment of multiple human diseases including …
demonstrated with great potential in the treatment of multiple human diseases including …
[HTML][HTML] Mesenchymal stem cell-derived exosomes: new opportunity in cell-free therapy
DP Sarvar, K Shamsasenjan… - Advanced …, 2016 - ncbi.nlm.nih.gov
Mesenchymal stromal/stem cells (MSCs) are involved in tissue homeostasis through direct
cell-to-cell interaction, as well as secretion of soluble factors. Exosomes are the sort of …
cell-to-cell interaction, as well as secretion of soluble factors. Exosomes are the sort of …
Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …
[HTML][HTML] Exosomes from adipose-derived stem cells inhibit inflammation and oxidative stress in LPS-acute kidney injury
W Zhang, J Zhang, H Huang - Experimental cell research, 2022 - Elsevier
Acute renal damage presents a significant danger to kidney health. Previous research has
found that acute kidney injury shows high levels of oxidative stress and inflammation caused …
found that acute kidney injury shows high levels of oxidative stress and inflammation caused …
Exosomes: emerging therapy delivery tools and biomarkers for kidney diseases
C Jin, P Wu, L Li, W Xu, H Qian - Stem cells international, 2021 - Wiley Online Library
Exosomes are nanometer‐sized small EVs coated with bilayer structure, which are released
by prokaryotic and eukaryotic cells. Exosomes are rich in a variety of biologically active …
by prokaryotic and eukaryotic cells. Exosomes are rich in a variety of biologically active …
Mesenchymal stem cell-derived extracellular vesicles to the rescue of renal injury
L Birtwistle, XM Chen, C Pollock - International Journal of Molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) and chronic kidney disease (CKD) are rising in global prevalence
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
Mesenchymal stem cell-derived exosomes: toward cell-free therapeutic strategies in chronic kidney disease
Q Cao, C Huang, XM Chen, CA Pollock - Frontiers in medicine, 2022 - frontiersin.org
Chronic kidney disease (CKD) is rising in global prevalence and has become a worldwide
public health problem, with adverse outcomes of kidney failure, cardiovascular disease, and …
public health problem, with adverse outcomes of kidney failure, cardiovascular disease, and …
[HTML][HTML] Mesenchymal stem cell-derived exosomes: Toward cell-free therapeutic strategies in regenerative medicine
ZJ Ma, JJ Yang, YB Lu, ZY Liu… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are multipotent stem cells with marked potential for
regenerative medicine because of their strong immunosuppressive and regenerative …
regenerative medicine because of their strong immunosuppressive and regenerative …