Corneal nerve loss is related to the severity of painful diabetic neuropathy

A Kalteniece, M Ferdousi, S Azmi… - European Journal of …, 2022 - Wiley Online Library
Background and purpose Previously it has been shown that patients with painful diabetic
neuropathy (PDN) have greater corneal nerve loss compared to patients with painless …

Early diagnosis of painful diabetic neuropathy by corneal confocal microscopy

H Wang, D Fan, S Zhang, X Wang - Zhonghua yi xue za zhi, 2014 - europepmc.org
Objective To explore the early diagnosis of painful diabetic neuropathy by observing the
alterations in corneal innervation with corneal confocal microscopy. Methods Fifty aged …

Diagnosis of neuropathy and risk factors for corneal nerve loss in type 1 and type 2 diabetes: a corneal confocal microscopy study

M Ferdousi, A Kalteniece, S Azmi… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE To assess the diagnostic utility of corneal confocal microscopy (CCM) for
diabetic peripheral neuropathy (DPN) and the risk factors for corneal nerve loss …

Augmented corneal nerve fiber branching in painful compared with painless diabetic neuropathy

S Püttgen, GJ Bönhof, A Strom, K Müssig… - The Journal of …, 2019 - academic.oup.com
Context The factors that determine the development of diabetic sensorimotor
polyneuropathy (DSPN) as a painful or painless entity are unknown. Objective We …

Diagnostic utility of corneal confocal microscopy and intra-epidermal nerve fibre density in diabetic neuropathy

U Alam, M Jeziorska, IN Petropoulos, O Asghar… - PloS one, 2017 - journals.plos.org
Objectives Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible
technique that quantifies small nerve fibres. We have compared the diagnostic capability of …

Utility of corneal confocal microscopy for assessing mild diabetic neuropathy: baseline findings of the LANDMark study

K Edwards, N Pritchard, D Vagenas… - Clinical and …, 2012 - Wiley Online Library
Background: For those in the field of managing diabetic complications, the accurate
diagnosis and monitoring of diabetic peripheral neuropathy (DPN) continues to be a …

Greater small nerve fibre damage in the skin and cornea of type 1 diabetic patients with painful compared to painless diabetic neuropathy

M Ferdousi, S Azmi, A Kalteniece… - European Journal of …, 2021 - Wiley Online Library
Background and aim Damage to small nociceptive fibres may contribute to painful diabetic
neuropathy. We aimed to compare large and small nerve fibre measurements together with …

Corneal confocal microscopy for assessment of diabetic peripheral neuropathy: a meta-analysis

MS Jiang, Y Yuan, ZX Gu, SL Zhuang - British Journal of …, 2016 - bjo.bmj.com
Purpose To evaluate the diagnostic performance of corneal confocal microscopy (CCM) in
assessing corneal nerve parameters in patients with diabetic peripheral neuropathy (DPN) …

Corneal confocal microscopy identifies people with type 1 diabetes with more rapid corneal nerve fibre loss and progression of neuropathy

U Alam, G Ponirakis, O Asghar, IN Petropoulos… - Journal of Clinical …, 2022 - mdpi.com
There is a need to accurately identify patients with diabetes at higher risk of developing and
progressing diabetic peripheral neuropathy (DPN). Fifty subjects with Type 1 Diabetes …

Diagnostic utility of corneal confocal microscopy in type 2 diabetic peripheral neuropathy

M Wang, C Zhang, A Zuo, L Li… - Journal of Diabetes …, 2021 - Wiley Online Library
Abstract Aims/Introduction The early pathological changes of diabetic peripheral neuropathy
(DPN) are mainly small nerve fiber injuries. Corneal confocal microscopy (CCM) is an easy …