Neurons are metabolically active cells with high energy demands. Thus, neurons are
particularly reliant on mitochondrial function, especially on the homeostasis properties of …

Mitochondrial dysregulation, such as mitochondrial complex I deficiency, increased
oxidative stress, perturbation of mitochondrial dynamics and mitophagy, has long been …

Neurodegeneration is among the most critical challenges that involve modern societies and
annually influences millions of patients worldwide. While the pathophysiology of Parkinson's …

Ischemic heart disease (IHD) is the leading cause of death and disability worldwide.
Therefore, novel therapeutic targets for protecting the heart against acute …

Parkinson's disease (PD) is a progressive neurodegenerative disease and is characterized
pathologically by selective loss of nigrostriatal dopaminergic neurons and the formation of …

Mitochondrial metabolism is a highly orchestrated phenomenon in which many enzyme
systems cooperate in a variety of pathways to dictate cellular fate. As well as its vital role in …

Parkinson's disease (PD) is a progressive neurological disorder marked by nigrostriatal
dopaminergic degeneration and development of cytoplasmic aggregates known as Lewy …

Mitochondria are small organelles that produce the majority of cellular energy as ATP.
Mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson's disease …

Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that
affects 1% of the population worldwide. Etiology of PD is likely to be multi-factorial such as …

Mitochondrial impairment is a well-established pathological pathway implicated in
Parkinson's disease (PD). Defects of the complex I of the mitochondrial respiratory chain …