[HTML][HTML] Systemic analysis of osteoblast-specific DNA methylation marks reveals novel epigenetic basis of osteoblast differentiation
F Yu, H Shen, HW Deng - Bone Reports, 2017 - Elsevier
DNA methylation is an important epigenetic modification that contributes to the lineage
commitment and specific functions of different cell types. In this study, we compared …
commitment and specific functions of different cell types. In this study, we compared …
[HTML][HTML] DNA methylation analysis identifies key transcription factors involved in mesenchymal stem cell osteogenic differentiation
GOMEZ, Rodolfo et al. DNA methylation analysis identifies key transcription factors involved
in mesenchymal stem cell osteogenic differentiation. Biol. Res.[online]. 2023, vol. 56, 9 …
in mesenchymal stem cell osteogenic differentiation. Biol. Res.[online]. 2023, vol. 56, 9 …
Comparative profiles of DNA methylation and differential gene expression in osteocytic areas from aged and young mice
Y Wei, J Fu, W Wu, J Wu - Cell Biochemistry and Function, 2020 - Wiley Online Library
Altered DNA methylation upon ageing may result in many age‐related diseases such as
osteoporosis. However, the changes in DNA methylation that occur in cortical bones, the …
osteoporosis. However, the changes in DNA methylation that occur in cortical bones, the …
Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation–can blood be used as a surrogate for bone?
P Ebrahimi, H Luthman, FE McGuigan, KE Akesson - Epigenetics, 2021 - Taylor & Francis
Difficulty in obtaining bone tissue is an obstacle to studying epigenetics to understand gene–
environment interactions, and their role in disease pathogenesis. Blood is an obvious …
environment interactions, and their role in disease pathogenesis. Blood is an obvious …
Genome‐wide DNA methylation analysis during osteogenic differentiation of human bone marrow mesenchymal stem cells
Y Cao, H Yang, L Jin, J Du, Z Fan - Stem cells international, 2018 - Wiley Online Library
Bone marrow mesenchymal stem cells (BMSCs) nowadays are regarded as promising
candidates in cell‐based therapy for the regeneration of damaged bone tissues that are …
candidates in cell‐based therapy for the regeneration of damaged bone tissues that are …
Genome‐wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis
J Delgado‐Calle, AF Fernández, J Sainz… - Arthritis & …, 2013 - Wiley Online Library
Objective To determine genome‐wide methylation profiles of bone from patients with hip
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures. Methods Trabecular bone …
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures. Methods Trabecular bone …
DNMT1 is a negative regulator of osteogenesis
C Tao, J Liu, Z Li, P Lai, S Zhang, J Qu, Y Tang… - Biology …, 2022 - journals.biologists.com
The role and underlying mechanisms of DNA methylation in osteogenesis/chondrogenesis
remain poorly understood. We here reveal DNA methyltransferase 1 (DNMT1), which is …
remain poorly understood. We here reveal DNA methyltransferase 1 (DNMT1), which is …
[HTML][HTML] DNA hypomethylation during MSC chondrogenesis occurs predominantly at enhancer regions
Regulation of transcription occurs in a cell type specific manner orchestrated by epigenetic
mechanisms including DNA methylation. Methylation changes may also play a key role in …
mechanisms including DNA methylation. Methylation changes may also play a key role in …
The influence of DNA methylation on bone cells
S Reppe, H Datta, KM Gautvik - Current genomics, 2015 - ingentaconnect.com
DNA methylation in eukaryotes invokes heritable alterations of the of the cytosine base in
DNA without changing the underlying genomic DNA sequence. DNA methylationmay be …
DNA without changing the underlying genomic DNA sequence. DNA methylationmay be …
[HTML][HTML] Epigenetic regulation during fetal femur development: DNA methylation matters
MC de Andrés, E Kingham, K Imagawa, A Gonzalez… - PloS one, 2013 - journals.plos.org
Epigenetic modifications are heritable changes in gene expression without changes in DNA
sequence. DNA methylation has been implicated in the control of several cellular processes …
sequence. DNA methylation has been implicated in the control of several cellular processes …