Continuous but not pulsed low-dose fetal betamethasone exposures extend the durability of antenatal steroid therapy
T Takahashi, Y Takahashi, EL Fee… - … of Physiology-Lung …, 2022 - journals.physiology.org
Antenatal steroid (ANS) therapy is the standard care for women at imminent risk of preterm
labor. Despite extensive and long-standing use, 40%–50% of babies exposed antenatally to …
labor. Despite extensive and long-standing use, 40%–50% of babies exposed antenatally to …
The duration of fetal antenatal steroid exposure determines the durability of preterm ovine lung maturation
Background Antenatal corticosteroids (ACS) are the standard of care for maturing the fetal
lung and improving outcomes for preterm infants. Antenatal corticosteroid dosing remains …
lung and improving outcomes for preterm infants. Antenatal corticosteroid dosing remains …
Variability in the efficacy of a standardized antenatal steroid treatment was independent of maternal or fetal plasma drug levels: evidence from a sheep model of …
Background Administration of antenatal steroids is standard of care for women assessed to
be at imminent risk of preterm delivery. There is a marked variation in antenatal steroid …
be at imminent risk of preterm delivery. There is a marked variation in antenatal steroid …
Effect of antenatal corticosteroid treatment on lung function in full-term newborn infants
O Hjalmarson, KL Sandberg - Neonatology, 2011 - karger.com
Background: Antenatal treatment of pregnant women with corticosteroids in order to
stimulate surfactant production has been shown to be effective. However, lung structure is …
stimulate surfactant production has been shown to be effective. However, lung structure is …
[HTML][HTML] Antenatal Corticosteroids: Extending the Practice for Late-Preterm and Scheduled Early-Term Deliveries?
ZT Htun, JC Hairston, C Gyamfi-Bannerman, J Marasch… - Children, 2021 - mdpi.com
Respiratory distress in late-preterm and early term infants generally may warrant admission
to a special care nursery or an intensive care unit. In particular, respiratory distress …
to a special care nursery or an intensive care unit. In particular, respiratory distress …
Antenatal corticosteroids for fetal lung maturity-too much of a good thing?
L Hrabalkova, T Takahashi, MW Kemp… - Current …, 2019 - ingentaconnect.com
Background: Between 5-15% of babies are born prematurely worldwide, with preterm birth
defined as delivery before 37 completed weeks of pregnancy (term is at 40 weeks of …
defined as delivery before 37 completed weeks of pregnancy (term is at 40 weeks of …
One percent of the clinical dose used for antenatal steroid therapy is sufficient to induce lung maturation when administered directly to the preterm ovine fetus
EL Fee, T Takahashi, Y Takahashi… - … of Physiology-Lung …, 2022 - journals.physiology.org
Antenatal steroids (ANSs) are routinely administered to women judged to be at imminent risk
of preterm delivery. Their principal benefit is precocious functional maturation of the preterm …
of preterm delivery. Their principal benefit is precocious functional maturation of the preterm …
Dose-response effects of betamethasone on maturation of the fetal sheep lung
M Loehle, M Schwab, S Kadner, KM Maner… - American journal of …, 2010 - Elsevier
OBJECTIVE: Glucocorticoid administration to women in preterm labor improves neonatal
mortality and morbidity. Fetal exposure to glucocorticoid levels higher than those …
mortality and morbidity. Fetal exposure to glucocorticoid levels higher than those …
[HTML][HTML] Antenatal corticosteroid administration for foetal lung maturation
Antenatal corticosteroids are an essential component in the management of women at risk
for preterm labour. They promote lung maturation and reduce the risk of other preterm …
for preterm labour. They promote lung maturation and reduce the risk of other preterm …
Antenatal corticosteroid treatment: factors other than lung maturation
K Haram, JH Mortensen, EF Magann… - The Journal of Maternal …, 2017 - Taylor & Francis
Antenatal corticosteroid (CS) therapy improves both fetal lung mechanism and gas
exchange due to accelerated morphologic development of type one and two pneumocytes …
exchange due to accelerated morphologic development of type one and two pneumocytes …