[HTML][HTML] Discriminating dominant computed tomography phenotypes in smokers without or with mild COPD

FAAM Hoesein, M Schmidt, OM Mets, HA Gietema… - Respiratory …, 2014 - Elsevier
Background Finding phenotypes within COPD patients may prove imperative for optimizing
treatment and prognosis. We hypothesized that it would be possible to discriminate …

[HTML][HTML] Identification of a predominant COPD phenotype in clinical practice

M Pistolesi, G Camiciottoli, M Paoletti, C Marmai… - Respiratory …, 2008 - Elsevier
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by airflow
limitation caused by small airways increased resistance and/or terminal airspaces …

A mixed phenotype of airway wall thickening and emphysema is associated with dyspnea and hospitalization for chronic obstructive pulmonary disease

N Van Tho, E Ogawa, LTH Trang, Y Ryujin… - Annals of the …, 2015 - atsjournals.org
Rationale: Quantitative computed tomography (CT) has been used to phenotype patients
with chronic obstructive pulmonary disease (COPD). A mixed phenotype is defined as the …

COPD phenotypes on computed tomography and its correlation with selected lung function variables in severe patients

SMD da Silva, IA Paschoal… - … journal of chronic …, 2016 - Taylor & Francis
Background Computed tomography (CT) phenotypic characterization helps in
understanding the clinical diversity of chronic obstructive pulmonary disease (COPD) …

[HTML][HTML] The role of CT scanning in multidimensional phenotyping of COPD

M Bafadhel, I Umar, S Gupta, JV Raj, DD Vara… - Chest, 2011 - Elsevier
Background COPD is a heterogeneous disease characterized by airflow obstruction and
diagnosed by lung function. CT imaging is emerging as an important, noninvasive tool in …

[HTML][HTML] Quantitative computed tomography in COPD: possibilities and limitations

OM Mets, PA De Jong, B Van Ginneken, HA Gietema… - Lung, 2012 - Springer
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that is
characterized by chronic airflow limitation. Unraveling of this heterogeneity is challenging …

Subtyping COPD by using visual and quantitative CT imaging features

J Park, BD Hobbs, JD Crapo, BJ Make, EA Regan… - Chest, 2020 - Elsevier
Background Multiple studies have identified COPD subtypes by using visual or quantitative
evaluation of CT images. However, there has been no systematic assessment of a combined …

Airway count and emphysema assessed by chest CT imaging predicts clinical outcome in smokers

AA Diaz, C Valim, T Yamashiro, RSJ Estépar, JC Ross… - Chest, 2010 - Elsevier
Background Recently, it has been shown that emphysematous destruction of the lung is
associated with a decrease in the total number of terminal bronchioles. It is unknown …

Computed tomography–based subclassification of chronic obstructive pulmonary disease

A Dirksen, MMW Wille - Annals of the American Thoracic Society, 2016 - atsjournals.org
Computed tomography (CT) is an obvious modality for subclassification of COPD.
Traditionally, the pulmonary involvement of chronic obstructive pulmonary disease (COPD) …

Clinical significance of radiologic characterizations in COPD

MLK Han, B Bartholmai, LX Liu, S Murray… - COPD: Journal of …, 2009 - Taylor & Francis
ABSTRACT COPD is a heterogeneous disorder with clinical assessment becoming
increasingly multidimensional. We hypothesized HRCT phenotype would strongly influence …