Sleep and waking function are closely connected in a 24-hour rhythm. The central nervous
system (CNS) structures involved in the promotion of the waking state include neurons …

Sleep and waking function are closely connected in a 24-hour rhythm. The central nervous
system (CNS) structures involved in the promotion of the waking state include neurons …

Drug-induced sleepiness is perhaps the most commonly reported side-effect of
pharmacologic agents active on the central nervous system (CNS): the 1990 Drug …

Medical practice of sleep medicine requires an extensive pharmacological knowledge,
especially when you need to make decisions about the drug scheme already adopted by a …

Sleep is a global, complex state that can be defined behaviorally or cognitively. The state of
sleep and its spectrum of electrophysiologic correlates are affected by medications in many …

Although considered a passive process in the past, it is now known that falling asleep and
passing through its various stages is an active process that is governed by certain groups of …

With an astounding 10% to 15% of the United States population meeting criteria for an
insomnia disorder, 1, 2 insomnia is not only the most common sleep disorder in the …

Insomnia is defined as inadequate or poor-quality sleep characterized by one or more of the
following: difficulty falling asleep, difficulty maintaining sleep, waking up too early in the …

CIRCADIAN RHYTHM AND HOMEOSTASIS Sleep and wakefulness are controlled by both
homeostatic and circadian factors. 1 The duration of prior wakefulness determines the …

Sleep states comprise a constellation of physiologic and behavioral traits, and the
mechanisms by which sedative/hypnotic medications alter these traits remain unclear. Drugs …