[HTML][HTML] Redox Mechanisms Underlying the Cytostatic Effects of Boric Acid on Cancer Cells—An Issue Still Open

G Paties Montagner, S Dominici, S Piaggi, A Pompella… - Antioxidants, 2023 - mdpi.com
Boric acid (BA) is the dominant form of boron in plasma, playing a role in different
physiological mechanisms such as cell replication. Toxic effects have been reported, both …

In vitro effects of boric acid on human liver hepatoma cell line (HepG2) at the half-maximal inhibitory concentration

A Tombuloglu, H Copoglu, Y Aydin-Son… - Journal of Trace Elements …, 2020 - Elsevier
Background Boron is a prominent part of the human diet and one of the essential trace
elements for humans. Dietary boron is mostly transformed into boric acid within the body and …

Boric acid affects cell proliferation, apoptosis, and oxidative stress in ALL cells

B Hilal, A Eldem, T Oz, M Pehlivan, I Pirim - Biological Trace Element …, 2023 - Springer
T-cell acute lymphoblastic leukemia (T-ALL) is a type of acute lymphoblastic leukemia from
early T-cell progenitors. Interest grows in creating less toxic agents and therapies for chemo …

Comparative effects of boric acid and calcium fructoborate on breast cancer cells

R Scorei, R Ciubar, CM Ciofrangeanu, V Mitran… - Biological trace element …, 2008 - Springer
Recent studies suggested that boron has a chemo-preventive role in prostate cancer. In the
present report, we investigated the effects of calcium fructoborate (CF) and boric acid (BA) …

Boric acid inhibits human prostate cancer cell proliferation

WT Barranco, CD Eckhert - Cancer letters, 2004 - Elsevier
The role of boron in biology includes coordinated regulation of gene expression in mixed
bacterial populations and the growth and proliferation of higher plants and lower animals …

Cytotoxic and apoptotic effects of boron compounds on leukemia cell line

Z Canturk, Y Tunali, S Korkmaz, Z Gulbaş - Cytotechnology, 2016 - Springer
In this study we investigated the effects of boric acid and sodium tetraborate on an acute
leukemia cell line and healthy human lymphocytes. We evaluated the effects of boric acid …

The importance of boron in biological systems

I Uluisik, HC Karakaya, A Koc - Journal of Trace Elements in Medicine and …, 2018 - Elsevier
Boron is an essential element for plants and probably essential for human and animal
health. Boron has a broad range of physiological effects on biological systems at low …

Boric acid exert anti-cancer effect in poorly differentiated hepatocellular carcinoma cells via inhibition of AKT signaling pathway

E Kahraman, E Göker - Journal of Trace Elements in Medicine and Biology, 2022 - Elsevier
Background The possible anti-cancer properties of boron, a trace element for humans, have
been demonstrated in various experimental and epidemiological studies, although the …

[PDF][PDF] Calcium fructoborate: plant-based dietary boron as potential medicine for cancer therapy

IR Scorei - Front Biosci (Schol Ed), 2011 - article.imrpress.com
[Frontiers in Bioscience S3, 205-215, January 1, 2011] 205 Calcium fructoborate: plant-based
dietary boron as potential medicine Page 1 [Frontiers in Bioscience S3, 205-215, January 1 …

Effect of tumor microenvironment on selective uptake of boric acid in HepG2 human hepatoma cells

YC Bai, YC Hsia, YT Lin, KH Chen, FI Chou… - Anticancer …, 2017 - ar.iiarjournals.org
Background: Feasibility and efficacy of boric acid (BA)-mediated boron neutron capture
therapy (BNCT) was first demonstrated by eliminating hepatocellular carcinoma (HCC) in a …