The role of il-1β on atrial fibrillation physiopathology

O Moreno-Loaiza, AR de Yurre Guirao, N Vera-Nuñez… - Biophysical …, 2020 - cell.com
Wednesday, February 19, 2020 569a group presented a higher number of arrhythmic
triggered events after a S1-S2 simulation protocol (Control= 1/10 vs. IL-1b= 7/13 mice). In …

The role of IL-6, IL-10, TNF-α and PD-1 expression on CD4 T cells in atrial fibrillation

W Bai, ZQ Liu, PY He - Heliyon, 2023 - cell.com
Backgrounds While not completely understood, the electrical, structural, and communication
pathways that play a role in the onset and progression of atrial fibrillation (AF) seem to be …

Proinflammatory cytokine modulates Intracellular calcium handling and Enhances ventricular arrhythmia susceptibility

YN Tsai, YW Hsiao, SF Lin, YH Chan… - Frontiers in …, 2021 - frontiersin.org
Background: The mechanism of Interleukin-17 (IL-17) induced ventricular arrhythmia (VA)
remains unclear. This study aimed to investigate the effect of intracellular calcium (Cai) …

Macrophage interleukin-1β mediates atrial fibrillation risk in diabetic mice

X Zhou, H Liu, F Feng, GJ Kang, M Liu, Y Guo… - JCI …, 2024 - Am Soc Clin Investig
Diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF). The
mechanisms underlying DM-associated AF are unclear. AF and DM are both related to …

Investigation of Key Cellular Targets in Atrial Fibrillation Induced Electromechanical Remodeling Using Human Atrial Cardiomyocytes Model

F Mazhar, C Bartolucci, C Corsi… - 2023 Computing in …, 2023 - ieeexplore.ieee.org
Atrial Fibrillation (AF) is the most common arrhythmia with a complex pathophysiology. In
experiments, it becomes quite challenging to dissect the key mechanisms behind the AF …

miR-190a-5p Partially Represses the Abnormal Electrical Activity of SCN3B in Cardiac Arrhythmias by Downregulation of IL-2

Q Li, Z Zhang, S Chen, Z Huang, M Wang… - Frontiers in …, 2022 - frontiersin.org
Cardiac arrhythmias (CAs) are generally caused by disruption of the cardiac conduction
system; interleukin-2 (IL-2) is a key player in the pathological process of CAs. This study …

Down-regulation of ATBF1 activates STAT3 signaling via PIAS3 in pacing-induced HL-1 atrial myocytes

Q Jiang, B Ni, J Shi, Z Han, R Qi, W Xu, D Wang… - Biochemical and …, 2014 - Elsevier
Atrial fibrillation (AF) is progressive and is the most common clinical arrhythmia. It is
associated with inflammatory changes characterized by signal transducer and activator of …

Calcium-activated potassium channels inhibition in autonomically stimulated human atrial myocytes

C Celotto, C Sánchez, P Laguna… - 2019 Computing in …, 2019 - ieeexplore.ieee.org
The autonomic nervous system has been reported to play a major role in the generation and
maintenance of atrial fibrillation. Various investigations have suggested small-conductance …

Atrial cardiomyopathy: pathophysiology and clinical consequences

A Goette, U Lendeckel - Cells, 2021 - mdpi.com
Around the world there are 33.5 million patients suffering from atrial fibrillation (AF) with an
annual increase of 5 million cases. Most AF patients have an established form of an atrial …

[HTML][HTML] Role of the interleukin-17 pathway in the pathogenesis of atrial fibrillation associated with inflammation

H Yue, J Gu, X Zhao, W Liang, Z Wu - Archives of Medical Science …, 2021 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is the most common clinical cardiovascular disease, and one of the
most important arrhythmia diseases; AF can increase the morbidity of stroke, arterial …