White matter tract integrity: an indicator of axonal pathology after mild traumatic brain injury

S Chung, E Fieremans, X Wang… - Journal of …, 2018 - liebertpub.com
We seek to elucidate the underlying pathophysiology of injury sustained after mild traumatic
brain injury (mTBI) using multi-shell diffusion magnetic resonance imaging, deriving …

Alterations in microstructure and local fiber orientation of white matter are associated with outcome after mild traumatic brain injury

M Mohammadian, T Roine, J Hirvonen… - Journal of …, 2020 - liebertpub.com
Mild traumatic brain injury (mTBI) can have long-lasting consequences. We investigated
white matter (WM) alterations at 6–12 months following mTBI using diffusion tensor imaging …

Investigating white matter tract microstructural changes at six–twelve weeks following mild traumatic brain injury: a combined diffusion tensor imaging and neurite …

LE Oehr, JYM Yang, J Chen, JJ Maller… - Journal of …, 2021 - liebertpub.com
Using diffusion-weighted imaging (DWI), research has demonstrated changes suggestive of
damage to white matter tracts (WMT) following mild traumatic brain injury (mTBI). Yet due to …

Quantifying white matter structural integrity with high-definition fiber tracking in traumatic brain injury

N Presson, D Krishnaswamy, L Wagener… - Military …, 2015 - academic.oup.com
There is an urgent, unmet demand for definitive biological diagnosis of traumatic brain injury
(TBI) to pinpoint the location and extent of damage. We have developed High-Definition …

White matter microstructure in chronic moderate‐to‐severe traumatic brain injury: Impact of acute‐phase injury‐related variables and associations with outcome …

AK Håberg, A Olsen, KG Moen… - Journal of …, 2015 - Wiley Online Library
This study examines how injury mechanisms and early neuroimaging and clinical measures
impact white matter (WM) fractional anisotropy (FA), mean diffusivity (MD), and tract volumes …

[HTML][HTML] High angular resolution diffusion-weighted imaging in mild traumatic brain injury

M Mohammadian, T Roine, J Hirvonen, T Kurki… - NeuroImage: Clinical, 2017 - Elsevier
We sought to investigate white matter abnormalities in mild traumatic brain injury (mTBI)
using diffusion-weighted magnetic resonance imaging (DW-MRI). We applied a global …

Traumatic brain injury: A comparison of diffusion and volumetric magnetic resonance imaging measures

NJ Bourke, M Yanez Lopez, PO Jenkins… - Brain …, 2021 - academic.oup.com
Cognitive impairment after traumatic brain injury remains hard to predict. This is partly
because axonal injury, which is of fundamental importance, is difficult to measure clinically …

Robust detection of traumatic axonal injury in individual mild traumatic brain injury patients: intersubject variation, change over time and bidirectional changes in …

ML Lipton, N Kim, YK Park, MB Hulkower… - Brain imaging and …, 2012 - Springer
To identify and characterize otherwise occult inter-individual spatial variation of white matter
abnormalities across mild traumatic brain injury (mTBI) patients. After informed consent and …

The evolution of white matter microstructural changes after mild traumatic brain injury: a longitudinal DTI and NODDI study

EM Palacios, JP Owen, EL Yuh, MB Wang… - Science …, 2020 - science.org
Neuroimaging biomarkers that can detect white matter (WM) pathology after mild traumatic
brain injury (mTBI) and predict long-term outcome are needed to improve care and develop …

Changes in apparent fiber density and track-weighted imaging metrics in white matter following experimental traumatic brain injury

DK Wright, LA Johnston, J Kershaw… - Journal of …, 2017 - liebertpub.com
Traumatic brain injury (TBI) has been assessed with diffusion tensor imaging (DTI), a
commonly used magnetic resonance imaging (MRI) marker for white matter integrity …