The Mammalian phosphatase of regenerating liver (PRL) family is primarily recognized for
its oncogenic properties. Here we found that in Drosophila, loss of prl-1 resulted in CO2 …

Neuroprotection is essential for the maintenance of normal physiological functions in the
nervous system. This is especially true under stress conditions. Here, we demonstrate a …

Background Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in
the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of …

Phosphatase of Regenerating Liver (PRL) family members have emerged as molecular
markers that significantly correlate to the ability of many cancers to metastasize. However …

Aberrant expression of members of the phosphatase of regenerating liver (PRL) family has
been implicated as a key factor in the progression of several forms of human cancers …

Abstract Phosphatase of Regenerating Liver (PRL) proteins regulate a number of important
cellular processes, including cell growth and division. Humans have three PRL proteins …

The phosphatase of regenerating liver (PRL) is a group of protein tyrosine phosphatases
that play a key role in cancer progression and metastasis. We previously showed that PRL-2 …

Background: Drosophila Phosphatase of Regenerating Liver-1 (PRL-1) is the only homolog
of the mammalian PRLs with which it shares high sequence and structural similarities. Whilst …

By the time a cancer metastasizes it has reached its most deadly stage. It therefore is
essential that the underpinning mechanisms promoting metastasis are understood …

Light at night has strong effects on physiology and behavior of mammals. It affects mood in
humans, which is exploited as light therapy, and has been shown to reset the circadian clock …