All classic, non-surgical anticancer approaches like chemotherapy, radiotherapy or
photodynamic therapy kill cancer cells by inducing severe oxidative stress. Even tough …

Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …

Oxidative stress is often considered as a causative factor in carcinogenesis. In addition,
current knowledge recognizes oxidative stress as a mechanism by which various cancer …

There are a number of intrinsic (eg oncogenes) and extrinsic (eg radiation and inflammation)
factors, which may arise in reactive oxygen species (ROS), resulting in DNA instability and …

Reactive oxygen species (ROS) are well known for their capacity to cause DNA damage,
augment mutagenesis, and thereby promote oncogenic transformation. Similarly, agents that …

Cancer is a global health problem responsible for one in six deaths worldwide. Treating
cancer has been a highly complex process. Conventional treatment approaches, such as …

Cancer cells are characterized by an increase in the rate of reactive oxygen species (ROS)
production and an altered redox environment compared to normal cells. Furthermore, redox …

The benevolent and detrimental effects of antioxidants are much debated in clinical trials
and cancer research. Several antioxidant enzymes and molecules are overexpressed in …

Tumor cells have deviated pathway that lead to increased constant state levels of free
radicals and consequently lead to DNA damage, and then activates signaling pathways that …

Oxidative stress is a key component in linking environmental toxicity to the multistage
carcinogenic process. Reactive oxygen species (ROS) are generated in response to both …